Pityriasis Rubra Pilaris: A Multicentric Case Series of 65 Spanish Patients.
Actas Dermosifiliogr
; 115(8): 761-765, 2024 Sep.
Article
en En, Es
| MEDLINE
| ID: mdl-38401879
ABSTRACT
INTRODUCTION:
PRP is a rare entity of unknown etiopathogenesis. Lack of management guidelines makes it a challenge for clinicians.OBJECTIVE:
To add our experience to increase evidence about PRP.METHODS:
We performed a retrospective, descriptive and multicentric study of 65 patients with PRP, being the largest European case series of patients with PRP.RESULTS:
PRP was more frequent in male patients with an average age of 51 years, but erythrodermic forms presented in older patients (average age 61 years). Six (75%) paediatric patients and ten (60%) non-erythrodermic adults controlled their disease with topical corticosteroids. On the contrary, 26 (68%) erythrodermic patients required biologic therapy as last and effective therapy line requiring an average of 6.5 months to achieve complete response.CONCLUSION:
Our study showed a statistical difference in terms of outcome and response to treatment between children or patients with limited disease and patients who develop erythroderma.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Pitiriasis Rubra Pilaris
Límite:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
País/Región como asunto:
Europa
Idioma:
En
/
Es
Revista:
Actas Dermosifiliogr
Año:
2024
Tipo del documento:
Article
Pais de publicación:
España