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Clinical and Radiographic Outcomes of Anterior Lumbar Interbody Fusions Using a Titanium Cage with a Biomimetic Surface.
Jowdy, Patrick K; Soliman, Mohamed A R; Quiceno, Esteban; Azmy, Shady; Popoola, Daniel O; Aguirre, Alexander O; Khan, Asham; Slosar, Paul J; Pollina, John; Mullin, Jeffrey P.
Afiliación
  • Jowdy PK; Department of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences at University at Buffalo, Buffalo, New York, United States.
  • Soliman MAR; Department of Neurosurgery, Buffalo General Medical Center, Kaleida Health, Buffalo, New York, United States.
  • Quiceno E; Department of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences at University at Buffalo, Buffalo, New York, United States.
  • Azmy S; Department of Neurosurgery, Buffalo General Medical Center, Kaleida Health, Buffalo, New York, United States.
  • Popoola DO; Department of Neurosurgery, Faculty of Medicine, Cairo University, Cairo, Egypt.
  • Aguirre AO; Department of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences at University at Buffalo, Buffalo, New York, United States.
  • Khan A; Department of Neurosurgery, Buffalo General Medical Center, Kaleida Health, Buffalo, New York, United States.
  • Slosar PJ; Jacobs School of Medicine and Biomedical Sciences at University at Buffalo, Buffalo, New York, United States.
  • Pollina J; Jacobs School of Medicine and Biomedical Sciences at University at Buffalo, Buffalo, New York, United States.
  • Mullin JP; Jacobs School of Medicine and Biomedical Sciences at University at Buffalo, Buffalo, New York, United States.
J Neurol Surg A Cent Eur Neurosurg ; 2024 May 22.
Article en En | MEDLINE | ID: mdl-38395054
ABSTRACT

BACKGROUND:

We analyzed clinical and radiographic outcomes in patients undergoing anterior lumbar interbody fusions (ALIFs) using a new biomimetic titanium fusion cage (Titan nanoLOCK interbody, Medtronic, Minneapolis, Minnesota, United States). This specialized cage employs precise nanotechnology to stimulate inherent biochemical and cellular osteogenic reactions to the implant, aiming to amplify the rate of fusion. To our knowledge, this is the only study to assess early clinical and radiographic results in ALIFs.

METHODS:

We conducted a retrospective review of data for patients who underwent single or multilevel ALIF using this implant between October 2016 and April 2021. Indications for treatment were spondylolisthesis, postlaminectomy syndrome, or spinal deformity. Clinical and radiographic outcome data for these patients were collected and assessed.

RESULTS:

A total of 84 patients were included. The mean clinical follow-up was 36.6 ± 14 months. At 6 months, solid fusion was seen in 97.6% of patients. At 12 months, solid fusion was seen in 98.8% of patients. Significant improvements were seen in patient-reported outcome measures (PROMs; visual analog scale and Oswestry Disability Index) at 6 and 12 months compared with the preoperative scores (p < 0.001). One patient required reoperation for broken pedicle screws 2 days after the ALIF. None of the patients required readmission within 90 days of surgery. No patients experienced an infection.

CONCLUSIONS:

ALIF using a new titanium interbody fusion implant with a biomimetic surface technology demonstrated high fusion rates (97.6%) as early as 6 months. There was significant improvement in PROMs at 6 and 12 months.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Neurol Surg A Cent Eur Neurosurg Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Alemania
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Neurol Surg A Cent Eur Neurosurg Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Alemania