Pulmonary salivary gland tumor-hyalinizing clear cell carcinoma: a literature review.

Wang, Xinyuan; Hu, Shumin; Lu, Hongyang

Wang, Xinyuan; Hu, Shumin; Lu, Hongyang.

Afiliación

Wang X; Zhejiang Key Laboratory of Diagnosis & Treatment Technology On Thoracic Oncology (Lung and Esophagus), Zhejiang Cancer Hospital, Hangzhou, 310022, Zhejiang, China.
Hu S; Department of Thoracic Medical Oncology, Zhejiang Cancer Hospital, Hangzhou, 310022, Zhejiang, China.
Lu H; Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, 310018, Zhejiang, China.

Diagn Pathol ; 19(1): 37, 2024 Feb 22.

Article en En | MEDLINE | ID: mdl-38389101

ABSTRACT

ABSTRACT

Primary pulmonary hyalinizing clear cell carcinoma (HCCC) is a very rare lung tumor that accounts for less than 0.09% of all primary lung tumors and has no specific epidemiology. The correct diagnosis requires imaging, laboratory, pathological, immunohistochemical, and molecular examination. The most typical feature of pulmonary HCCC is the clear cell component with clear stroma. In addition, the fusion gene EWSR1ATF1 due to t(12;22)(q13;q12) is essential for the pathological diagnosis of pulmonary HCCC. The main treatment for pulmonary HCCC is surgery. This review focus on the pathological features, immunohistochemical examination, mutation analysis and treatment of pulmonary HCCC.

Asunto(s)

Adenocarcinoma de Células Claras; Carcinoma; Neoplasias Pulmonares; Neoplasias de las Glándulas Salivales; Humanos; Neoplasias de las Glándulas Salivales/diagnóstico; Neoplasias de las Glándulas Salivales/genética; Neoplasias de las Glándulas Salivales/patología; Neoplasias Pulmonares/genética; Adenocarcinoma de Células Claras/diagnóstico; Adenocarcinoma de Células Claras/genética; Adenocarcinoma de Células Claras/patología

Palabras clave

EWSR::ATF1; Molecular characteristics; Pathology; Pulmonary HCCC

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de las Glándulas Salivales / Carcinoma / Adenocarcinoma de Células Claras / Neoplasias Pulmonares Límite: Humans Idioma: En Revista: Diagn Pathol Asunto de la revista: PATOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

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