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Gonadotropin-inhibitory hormone and its receptors in teleosts: Physiological roles and mechanisms of actions.
Wang, Bin; Paullada-Salmerón, José A; Muñoz-Cueto, José A.
Afiliación
  • Wang B; State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao 266071, China; Laboratory for Marine Fisheries Science and Food Production Processes, Laoshan Laboratory, Qingdao 266237, China; Department of Biology, Faculty of Marine and Environmental Sciences, University of Cádiz, Puerto Real (Cádiz), Spain.
  • Paullada-Salmerón JA; Department of Biology, Faculty of Marine and Environmental Sciences, University of Cádiz, Puerto Real (Cádiz), Spain; Marine Research Institute (INMAR), Marine Campus of International Excellence (CEIMAR) and Agrifood Campus of International Excellence (ceiA3), Puerto Real (Cádiz), Spain; The European University of the Seas (SEA-EU), Cádiz, Spain.
  • Muñoz-Cueto JA; Department of Biology, Faculty of Marine and Environmental Sciences, University of Cádiz, Puerto Real (Cádiz), Spain; Marine Research Institute (INMAR), Marine Campus of International Excellence (CEIMAR) and Agrifood Campus of International Excellence (ceiA3), Puerto Real (Cádiz), Spain; The European University of the Seas (SEA-EU), Cádiz, Spain. Electronic address: munoz.cueto@uca.es.
Gen Comp Endocrinol ; 350: 114477, 2024 05 01.
Article en En | MEDLINE | ID: mdl-38387532
ABSTRACT
Gonadotropin-inhibitory hormone (GnIH) was the first reported hypothalamic neuropeptide inhibiting reproduction in vertebrates. Since its discovery in the quail brain, its orthologs have been identified in a variety of vertebrate species and even protochordates. Depending on the species, the GnIH precursor polypeptides comprise two, three or four mature peptides of the RFamide family. It has been well documented that GnIH inhibits reproduction at the brain-pituitary-gonadal levels and participates in metabolism, stress response, and social behaviors in birds and mammals. However, most studies in fish have mainly been focused on the physiological roles of GnIH in the control of reproduction and results obtained are in some cases conflicting, leaving aside its potential roles in the regulation of other functions. In this manuscript we summarize the information available in fish with respect to the structural diversity of GnIH peptides and functional roles of GnIH in reproduction and other physiological processes. We also highlight the molecular mechanisms of GnIH actions on target cells and possible interactions with other neuroendocrine factors.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Gonadotropinas / Hormonas Hipotalámicas Límite: Animals Idioma: En Revista: Gen Comp Endocrinol Año: 2024 Tipo del documento: Article País de afiliación: España Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Gonadotropinas / Hormonas Hipotalámicas Límite: Animals Idioma: En Revista: Gen Comp Endocrinol Año: 2024 Tipo del documento: Article País de afiliación: España Pais de publicación: Estados Unidos