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Predictive value of serum albumin and calcium levels in burn patients with Pseudomonas aeruginosa infection: A comprehensive analysis of clinical outcomes.
Haghighi Bardineh, Seyed Ashkan; Balou, Heydar Ali; Sedigh Ebrahim-Saraie, Hadi; Mobayen, Mohammadreza; Esmailzadeh, Mojdeh; Haghighi, Samane; Haghighi, Arezoo; Sadeghi, Mahsa.
Afiliación
  • Haghighi Bardineh SA; Burn and Regenerative Medicine Research Center, Guilan University of Medical Sciences, Rasht, Iran.
  • Balou HA; Razi Clinical Research Development Unit, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran.
  • Sedigh Ebrahim-Saraie H; Razi Clinical Research Development Unit, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran.
  • Mobayen M; Department of Microbiology, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
  • Esmailzadeh M; Burn and Regenerative Medicine Research Center, Guilan University of Medical Sciences, Rasht, Iran.
  • Haghighi S; Burn and Regenerative Medicine Research Center, Guilan University of Medical Sciences, Rasht, Iran.
  • Haghighi A; Institute of Theoretical and Translational Medicine, Semmelweis University, Budapest, Hungary.
  • Sadeghi M; Department of Pharmacology and Pharmacotherapy, Faculty of Pharmaceutical Sciences, Semmelweis University, Budapest, Hungary.
Int Wound J ; 21(3): e14786, 2024 Mar.
Article en En | MEDLINE | ID: mdl-38385765
ABSTRACT
In the ongoing challenge to reduce burn-associated mortality rates, this study explores the predictive capacity of clinical factors in burn patients, focusing on vitamin D, calcium, and serum albumin levels during hospitalisation in cases with Pseudomonas aeruginosa infection. Our research involves a comprehensive analysis of 100 burn patients, encompassing crucial clinical parameters such as the burn severity index, serum albumin, vitamin D, and calcium levels at admission. Data were meticulously entered into IBM Statistics SPSS software version 28 and subjected to statistical analysis. The study reveals an average patient age of 39.75 years and a notable 34% mortality rate. Additionally, the average lengths of hospital and intensive care unit (ICU) stays are determined to be 11.33 and 7.79 days, respectively. Significantly, a correlation between calcium and albumin variables and treatment outcomes is established, showcasing their potential to predict variable changes in patient mortality rates. Furthermore, a noteworthy association is observed between serum calcium levels and the duration of ICU hospitalisation. In conclusion, albumin and calcium variables emerge as sensitive and specific indicators for predicting outcomes in burn patients. Importantly, the independence of these factors from the physician's experience and diagnosis reduces human error and thus increases the accuracy of mortality prediction in this patient population.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por Pseudomonas / Quemaduras Límite: Adult / Humans Idioma: En Revista: Int Wound J Año: 2024 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por Pseudomonas / Quemaduras Límite: Adult / Humans Idioma: En Revista: Int Wound J Año: 2024 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Reino Unido