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Novel recruitment approaches and operational results for a statewide population Cohort for cancer research: The Healthy Oregon Project.
Zhang, Zhenzhen; Shafer, Autumn; Johnson-Camacho, Katie; Adey, Andrew; Anur, Pavana; Brown, Kim A; Conrad, Casey; Crist, Rachel; Farris, Paige E; Harrington, Christina A; Marriott, Lisa K; Mitchell, Asia; O'Roak, Brian; Serrato, Vanessa; Richards, C Sue; Spellman, Paul T; Shannon, Jackilen.
Afiliación
  • Zhang Z; Division of Oncological Sciences, Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.
  • Shafer A; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.
  • Johnson-Camacho K; School of Journalism and Communication, University of Oregon, Eugene, OR, USA.
  • Adey A; Department of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
  • Anur P; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.
  • Brown KA; Cancer Early Detection Advanced Research Center, Oregon Health and Science University, Portland, OR, USA.
  • Conrad C; Division of Oncological Sciences, Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.
  • Crist R; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.
  • Farris PE; Cancer Early Detection Advanced Research Center, Oregon Health and Science University, Portland, OR, USA.
  • Harrington CA; Department of Molecular and Medical Genetics, Oregon Health and Science University, Portland, OR, USA.
  • Marriott LK; Knight Cardiovascular Institute, Oregon Health and Science University, Portland, OR, USA.
  • Mitchell A; Cancer Early Detection Advanced Research Center, Oregon Health and Science University, Portland, OR, USA.
  • O'Roak B; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.
  • Serrato V; Oregon Clinical and Translational Research Institute, Oregon Health & Science University, Portland, OR, USA.
  • Richards CS; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.
  • Spellman PT; Cancer Early Detection Advanced Research Center, Oregon Health and Science University, Portland, OR, USA.
  • Shannon J; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.
J Clin Transl Sci ; 8(1): e32, 2024.
Article en En | MEDLINE | ID: mdl-38384895
ABSTRACT

Background:

Cancer health research relies on large-scale cohorts to derive generalizable results for different populations. While traditional epidemiological cohorts often use costly random sampling or self-motivated, preselected groups, a shift toward health system-based cohorts has emerged. However, such cohorts depend on participants remaining within a single system. Recent consumer engagement models using smartphone-based communication, driving projects, and social media have begun to upend these paradigms.

Methods:

We initiated the Healthy Oregon Project (HOP) to support basic and clinical cancer research. HOP study employs a novel, cost-effective remote recruitment approach to effectively establish a large-scale cohort for population-based studies. The recruitment leverages the unique email account, the HOP website, and social media platforms to direct smartphone users to the study app, which facilitates saliva sample collection and survey administration. Monthly newsletters further facilitate engagement and outreach to broader communities.

Results:

By the end of 2022, the HOP has enrolled approximately 35,000 participants aged 18-100 years (median = 44.2 years), comprising more than 1% of the Oregon adult population. Among those who have app access, ∼87% provided consent to genetic screening. The HOP monthly email newsletters have an average open rate of 38%. Efforts continue to be made to improve survey response rates.

Conclusion:

This study underscores the efficacy of remote recruitment approaches in establishing large-scale cohorts for population-based cancer studies. The implementation of the study facilitates the collection of extensive survey and biological data into a repository that can be broadly shared and supports collaborative clinical and translational research.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Clin Transl Sci Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Clin Transl Sci Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido