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Evaluation of the GeneXpert MTB/RIF to diagnose tuberculosis in a public health laboratory.
Arbués, Mohanna Damasceno; Rossetti, Maria Lúcia Rosa.
Afiliación
  • Arbués MD; Universidade Luterana do Brasil. Programa de Doutorado em Biologia Molecular e Celular Aplicada à Saúde. Canoas, RS, Brasil.
  • Rossetti MLR; Universidade Luterana do Brasil. Programa de Doutorado em Biologia Molecular e Celular Aplicada à Saúde. Canoas, RS, Brasil.
Rev Saude Publica ; 58: 03, 2024.
Article en En | MEDLINE | ID: mdl-38381893
ABSTRACT

OBJECTIVES:

To evaluate the performance of geneXpert MTB/Rif versus conventional methods (bacilloscopy and culture) in the diagnosis of tuberculosis in a Central Public Health Laboratory (LACEN, Tocantins), Northern Brazil.

METHODS:

Retrospective study, with information from 1,973 suspected cases of tuberculosis from patients treated from January 2015 to December 2020.

RESULTS:

From the culture (reference standard), the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of the geneXpert MTB/Rif were 100%, 97%, 74%, 100%, and 97%, respectively, against 85%, 98%, 80%, 98%, and 97% of bacilloscopy.

CONCLUSIONS:

The geneXpert MTB/Rif performed similarly to culture and better than bacilloscopy. Although positive cases with negative culture should be evaluated with caution, its routine use is important for the early detection of tuberculosis.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tuberculosis / Mycobacterium tuberculosis Límite: Humans País/Región como asunto: America do sul / Brasil Idioma: En Revista: Rev Saude Publica Año: 2024 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Brasil
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tuberculosis / Mycobacterium tuberculosis Límite: Humans País/Región como asunto: America do sul / Brasil Idioma: En Revista: Rev Saude Publica Año: 2024 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Brasil