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Long-Term Outcomes of Mechanical Versus Bioprosthetic Aortic Valve Replacement: A Systematic Review and Meta-Analysis.
Vankayalapati, Dilip K; Segun-Omosehin, Omotayo; El Ghazal, Nour; Suresh Daniel, Rohan; El Haddad, Joe; Mansour, Rania; Yap, Nathanael; Miangul, Shahid; Nakanishi, Hayato; Than, Christian A.
Afiliación
  • Vankayalapati DK; General Surgery, Buckinghamshire Healthcare NHS Trust, Buckinghamshire, GBR.
  • Segun-Omosehin O; Cardiothoracic Surgery, St George's University of London, London, GBR.
  • El Ghazal N; Cardiothoracic Surgery, University of Nicosia Medical School, Nicosia, CYP.
  • Suresh Daniel R; Cardiothoracic Surgery, St George's University of London, London, GBR.
  • El Haddad J; Cardiothoracic Surgery, University of Nicosia Medical School, Nicosia, CYP.
  • Mansour R; Cardiothoracic Surgery, St George's University of London, London, GBR.
  • Yap N; Cardiothoracic Surgery, University of Nicosia Medical School, Nicosia, CYP.
  • Miangul S; Cardiothoracic Surgery, St George's University of London, London, GBR.
  • Nakanishi H; Cardiothoracic Surgery, University of Nicosia Medical School, Nicosia, CYP.
  • Than CA; Cardiothoracic Surgery, St George's University of London, London, GBR.
Cureus ; 16(1): e52550, 2024 Jan.
Article en En | MEDLINE | ID: mdl-38371071
ABSTRACT
This study aimed to investigate the safety and efficacy of bioprosthetic (BV) versus mechanical valves (MV) on long-term outcomes in 50- to 70-year-old aortic stenosis (AS) patients. A literature search for articles published until April 2023 yielded 13 eligible studies, with 15,320 patients divided into BV (n = 7,320) and MV (n = 8,000) cohorts. The review was registered prospectively with PROSPERO (CRD42021278777). MV demonstrated a favorable hazard ratio (HR 1.12, 95% CI 1.00-1.25, I2 = 60%) and higher survival rates at 5 (OR1.13, 95% CI 1.02-1.25, I2 = 42%) and 10 years (OR 1.13, 95% CI 1.05-1.23, I2 = 0%). At 15 years, stroke incidence was comparable (OR 1.12, 95% CI 0.98-1.27, I2 = 4%). BV showed lower bleeding events (OR 1.7, 95% CI 1.18-2.46, I2 = 88%), but MV replacement showed lower reoperation incidence (OR 0.27, 95% CI 0.18-0.42, I2 = 85%). MV appears favorable for the long-term approach in AS management compared to BV.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cureus Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cureus Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos