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Risk of cardiovascular disease decreases over time in psoriatic arthritis but not in spondylarthritis: meta-analysis of longitudinal studies.
Gouze, Hélène; Aegerter, Philippe; Gouyette, Yasmine; Breban, Maxime; D'Agostino, Maria Antonietta.
Afiliación
  • Gouze H; Rheumatology Department, Ambroise Paré Hospital, AP-HP-Paris Saclay, Boulogne, France.
  • Aegerter P; Centre for Research in Epidemiology and Population Health, U1018, Paris Saclay University, Paris, France.
  • Gouyette Y; Centre for Research in Epidemiology and Population Health, U1018, Paris Saclay University, Paris, France.
  • Breban M; Epidemiology and Public Health Service, Hôpitaux Universitaires Paris-Saclay, Le Kremlin-Bicêtre, France.
  • D'Agostino MA; Rheumatology Department, Ambroise Paré Hospital, AP-HP-Paris Saclay, Boulogne, France.
Rheumatology (Oxford) ; 63(10): 2638-2647, 2024 Oct 01.
Article en En | MEDLINE | ID: mdl-38366949
ABSTRACT

OBJECTIVE:

SpA and PsA represent two frequent inflammatory rheumatic disorders characterized by an increased burden on quality of life due to the association of several comorbidities, especially cardiovascular disease (CVD). The estimated prevalence of CVD ranges from 12 to 19% and differs between the two diseases, however, the incidence of CVD is not completely known. We aimed to systematically review the literature and perform a meta-analysis of controlled observational studies to assess the incidence rate of CVD over time in SpA and PsA.

METHODS:

We performed a systematic literature review (SLR) of longitudinal studies with a study period of at least 5 years, including SpA/PsA patients and general population. The main outcome was the occurrence of CVD, including ischaemic heart disease, stroke and death from CV causes. We then performed a random-effects model for meta-analysis.

RESULTS:

The SLR included 34 articles, mainly focused on the association between SpA/PsA and CVD. Twenty-four articles were then selected for the meta-analysis. The overall incidence of CVD was increased in PsA [hazard ratio (HR) 1.28 (95% CI 1.15, 1.43)] and in SpA [HR 1.45 (95% CI 1.22, 1.72)] compared with the general population, with consistency across the different types of CVDs. Interestingly the incidence tended to decrease over time in PsA but not in SpA.

CONCLUSION:

The SLR and meta-analysis confirmed the increased incidence of CVD in both SpA and PsA patients compared with the general population, although the increase seems to be less prominent in PsA than in SpA. Future studies are needed to confirm our findings.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades Cardiovasculares / Artritis Psoriásica / Espondiloartritis Límite: Humans Idioma: En Revista: Rheumatology (Oxford) Asunto de la revista: REUMATOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades Cardiovasculares / Artritis Psoriásica / Espondiloartritis Límite: Humans Idioma: En Revista: Rheumatology (Oxford) Asunto de la revista: REUMATOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Reino Unido