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Pilot Study of Intensive Trismus Intervention Using Restorabite™ During Unilateral Adjuvant Radiation for Head and Neck Cancer.
Charters, Emma; Loy, Jamie; Wu, Raymond; Cheng, Kai; Dunn, Masako; Davies, Sarah; Clark, Jonathan.
Afiliación
  • Charters E; Department of Head and Neck Surgery, Chris O'Brien Lifehouse, 119-143 Missenden Road, Sydney, NSW, 2050, Australia. Emma.Charters@lh.org.au.
  • Loy J; School of Health Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia. Emma.Charters@lh.org.au.
  • Wu R; Department of Head and Neck Surgery, Chris O'Brien Lifehouse, 119-143 Missenden Road, Sydney, NSW, 2050, Australia.
  • Cheng K; Department of Radiation Oncology, Chris O'Brien Lifehouse, Sydney, NSW, Australia.
  • Dunn M; Sydney Medical School, Faculty of Medicine and Health Sciences, The University of Sydney, Sydney, NSW, Australia.
  • Davies S; Department of Head and Neck Surgery, Chris O'Brien Lifehouse, 119-143 Missenden Road, Sydney, NSW, 2050, Australia.
  • Clark J; Royal Prince Alfred Institute of Academic Surgery, Sydney Local Health District, Sydney, NSW, Australia.
Dysphagia ; 39(5): 864-871, 2024 Oct.
Article en En | MEDLINE | ID: mdl-38366084
ABSTRACT
Trismus commonly arises after surgery for head and neck cancer (HNC) and its severity is potentiated by postoperative radiotherapy. While the benefit of trismus rehabilitation after surgery and radiotherapy is well established, the evidence during radiotherapy is less clear. This may be due to poor adherence to trismus exercises secondary to acute mucositis. This study assessed the feasibility of using a novel trismus device during adjuvant radiotherapy for HNC in patients with acute postoperative trismus. Prospective single-arm cohort feasibility study. Eligible patients had undergone surgery with curative intent for HNC, planned for adjuvant radiotherapy, and were suitable for trismus rehabilitation. Participants completed a 10-week exercise program using a novel jaw stretching device. Study outcomes were adherence, maximal incisal opening (MIO), and trismus-related function and quality of life scores, assessed at baseline, 10 weeks, and 6 months after commencing exercises. Nine patients diagnosed with trismus after primary surgery were recruited. The mean increase in MIO at 10 weeks was 7.8 mm (range -4 to 15 mm, p = 0.03), and at 6 months was 10.6 mm (range 1-26 mm, p = 0.03). Significant improvements were observed in trismus-related quality of life (Gothenburg Trismus Questionnaire; p = 0.04). Adherence to the exercises was 100% in week 1-2, 67% in weeks 3-6, and 100% at 10 weeks (1 month post radiation). This study demonstrates the feasibility of using a novel jaw stretching device during adjuvant radiotherapy. Further evaluation is warranted to assess the effectiveness of early intervention and prevention of trismus during HNC radiotherapy.Level of Evidence IV.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Calidad de Vida / Trismo / Estudios de Factibilidad / Neoplasias de Cabeza y Cuello Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Dysphagia Asunto de la revista: GASTROENTEROLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Calidad de Vida / Trismo / Estudios de Factibilidad / Neoplasias de Cabeza y Cuello Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Dysphagia Asunto de la revista: GASTROENTEROLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Estados Unidos