Diagnostic Performance Using a Combination of MRI Findings for Evaluating Cognitive Decline.
J Korean Soc Radiol
; 85(1): 184-196, 2024 Jan.
Article
en En
| MEDLINE
| ID: mdl-38362402
ABSTRACT
Purpose:
We investigated potentially promising imaging findings and their combinations in the evaluation of cognitive decline. Materials andMethods:
This retrospective study included 138 patients with subjective cognitive impairments, who underwent brain MRI. We classified the same group of patients into Alzheimer's disease (AD) and non-AD groups, based on the neuropsychiatric evaluation. We analyzed imaging findings, including white matter hyperintensity (WMH) and cerebral microbleeds (CMBs), using the Kruskal-Wallis test for group comparison, and receiver operating characteristic (ROC) curve analysis for assessing the diagnostic performance of imaging findings.Results:
CMBs in the lobar or deep locations demonstrated higher prevalence in the patients with AD compared to those in the non-AD group. The presence of lobar CMBs combined with periventricular WMH (area under the ROC curve [AUC] = 0.702 [95% confidence interval 0.599-0.806], p < 0.001) showed the highest performance in differentiation of AD from non-AD group.Conclusion:
Combinations of imaging findings can serve as useful additive diagnostic tools in the assessment of cognitive decline.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Idioma:
En
Revista:
J Korean Soc Radiol
Año:
2024
Tipo del documento:
Article
Pais de publicación: