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Genomic island-encoded regulatory proteins in enterohemorrhagic Escherichia coli O157:H7.
Wang, Fang; Sun, Hongmin; Kang, Chenbo; Yan, Jun; Chen, Jingnan; Feng, Xuequan; Yang, Bin.
Afiliación
  • Wang F; TEDA Institute of Biological Sciences and Biotechnology, Nankai University, Tianjin, China.
  • Sun H; Intensive Care Unit, Shenzhen Institute of Translational Medicine, Health Science Center, The First Affiliated Hospital of Shenzhen University, Shenzhen, China.
  • Kang C; TEDA Institute of Biological Sciences and Biotechnology, Nankai University, Tianjin, China.
  • Yan J; TEDA Institute of Biological Sciences and Biotechnology, Nankai University, Tianjin, China.
  • Chen J; TEDA Institute of Biological Sciences and Biotechnology, Nankai University, Tianjin, China.
  • Feng X; TEDA Institute of Biological Sciences and Biotechnology, Nankai University, Tianjin, China.
  • Yang B; Tianjin First Central Hospital, Nankai University, Tianjin, China.
Virulence ; 15(1): 2313407, 2024 12.
Article en En | MEDLINE | ID: mdl-38357901
ABSTRACT
Enterohemorrhagic Escherichia coli (EHEC) is an important zoonotic pathogen that is a major cause of foodborne diseases in most developed and developing countries and can cause uncomplicated diarrhoea, haemorrhagic colitis, and haemolytic uraemic syndrome. O islands (OIs), which are unique genomic islands in EHEC O157H7, are composed of 177 isolated genomic features and harbour 26% of the total genes that are absent in the non-pathogenic E. coli K-12 genome. In the last twenty years, many OI-encoded proteins have been characterized, including proteins regulating virulence, motility, and acid resistance. Given the critical role of regulatory proteins in the systematic and hierarchical regulation of bacterial biological processes, this review summarizes the OI-encoded regulatory proteins in EHEC O157H7 characterized to date, emphasizing OI-encoded regulatory proteins for bacterial virulence, motility, and acid resistance. This summary will be significant for further exploration and understanding of the virulence and pathogenesis of EHEC O157H7.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Escherichia coli O157 / Proteínas de Escherichia coli / Infecciones por Escherichia coli / Escherichia coli Enterohemorrágica Límite: Humans Idioma: En Revista: Virulence Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Escherichia coli O157 / Proteínas de Escherichia coli / Infecciones por Escherichia coli / Escherichia coli Enterohemorrágica Límite: Humans Idioma: En Revista: Virulence Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos