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Fast, sustainable, and simultaneous analysis of water- and fat-soluble vitamins by the two-dimensional microcarbon fiber fractionation system hyphenated with MS detection.
Fatima, Zakia; Wang, Liyuan; Cui, Meiyu; Jin, Xiangzi; Liu, Lu; Li, Donghao.
Afiliación
  • Fatima Z; Department of Chemistry, Yanbian University, Park Road 977, Yanji, 133002, Jilin Province, PR China.
  • Wang L; Department of Chemistry, Yanbian University, Park Road 977, Yanji, 133002, Jilin Province, PR China.
  • Cui M; Department of Chemistry, Yanbian University, Park Road 977, Yanji, 133002, Jilin Province, PR China.
  • Jin X; Department of Chemistry, Yanbian University, Park Road 977, Yanji, 133002, Jilin Province, PR China.
  • Liu L; Pathology and Pathophysiology, Medical College, Yanbian University, Park Road 977, Yanji City, 133002, Jilin Province, PR China.
  • Li D; Department of Chemistry, Yanbian University, Park Road 977, Yanji, 133002, Jilin Province, PR China; Chemistry Department, Interdisciplinary Program of Biological Functional Molecules, College of Integration Science, Yanbian University, Park Road 977, Yanji City, 133002, Jilin Province, PR China. El
Anal Chim Acta ; 1295: 342288, 2024 Mar 22.
Article en En | MEDLINE | ID: mdl-38355222
ABSTRACT

BACKGROUND:

Vitamins are micronutrients that are required for normal growth and development of living organisms. However, due to their various chemical properties (e.g., acid-base behavior, the presence of numerous forms) and fluctuating concentration levels within complex matrices, simultaneous analysis of multi-class vitamins, including their active forms, is a challenging task. The growing nutrient shortage in foods is concerning for food consumers, manufacturers, and quality control organizations. Hence, a simple, fast, and greener approach that can simultaneously analyze multi-class vitamins is required to aid food testing and clinical laboratories in evaluating vitamin content more rapidly and accurately.

RESULTS:

A green and rapid analytical method based on online two-dimensional microscale carbon fiber/activated carbon fiber fractionation-mass spectrometry (2DµCFs-MS) was developed and validated for simultaneous determination of vitamins (water- and fat-soluble vitamins and some analogs) in food supplements and fortified energy drinks. Vitamins have been successfully separated into three different fractions using the minimum toxic solvent (only 0.7 mL of organic solvent) in a single run within 6 min. The limit of detection (LOD) ranges from 0.1 to 10.4 ng/mL, and the limit of quantification (LOQ) ranges from 0.39 to 34.5 ng/mL. The method also showed adequate repeatability and intermediate precision, with RSD<10 % and R2 > 0.99 for most vitamins. The analytical method was evaluated in terms of greenness, with an analytical greenness (AGREE) score of 0.68.

SIGNIFICANCE:

The 2DµCFs-MS system was developed to separate and detect multi-class vitamins simultaneously, which can be used as a beneficial tool to investigate vitamin content for food labeling and determining the vitamins in biological fluids and other complex samples. The developed method can tackle the challenge of simultaneous and fast routine analysis of multi-class vitamins.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vitaminas / Agua Tipo de estudio: Diagnostic_studies Idioma: En Revista: Anal Chim Acta Año: 2024 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vitaminas / Agua Tipo de estudio: Diagnostic_studies Idioma: En Revista: Anal Chim Acta Año: 2024 Tipo del documento: Article Pais de publicación: Países Bajos