Your browser doesn't support javascript.
loading
2-Hydroxyethyl methacrylate (2-HEMA) sensitization, a global epidemic at its peak in Spain?
Gatica-Ortega, Maria Elena; Pastor-Nieto, Maria Antonia; Giménez-Arnau, Ana María; Mercader-García, Pedro; Sanz-Sánchez, Tatiana; Carrascosa-Carrillo, José Manuel; Córdoba-Guijarro, Susana; Sánchez-Pérez, Javier; Silvestre, Juan Francisco; Frutos, Francisco Javier Ortiz-de; Tous-Romero, Fátima; Fernández-Redondo, Virginia; Serra-Baldrich, Esther; Ruíz-González, Inmaculada; González Pérez, Ricardo; Miquel-Miquel, Javier; Guillén, Paloma Sánchez-Pedreño; Hervella-García, Marcos; Heras-Mendaza, Felipe; Gómez-de-la-Fuente, Enrique; Zaragoza-Ninet, Violeta; Gilo, Araceli Sánchez; Rodríguez-Serna, Mercedes; Melé-Ninot, Gemma; Descalzo, Miguel Ángel; de-Vega, Marina; García-Doval, Ignacio; Borrego, Leopoldo.
Afiliación
  • Gatica-Ortega ME; Dermatology Department, Complejo Hospitalario Universitario de Toledo, Toledo, Spain.
  • Pastor-Nieto MA; Escuela Internacional de Doctorado, Universidad de Castilla-La-Mancha, Toledo, Spain.
  • Giménez-Arnau AM; Escuela Internacional de Doctorado, Universidad de Castilla-La-Mancha, Toledo, Spain.
  • Mercader-García P; Dermatology Department, Hospital Universitario de Guadalajara, Guadalajara, Spain.
  • Sanz-Sánchez T; Dermatology Department, Hospital Universitario Fundacion Jiménez Díaz, Madrid, Spain.
  • Carrascosa-Carrillo JM; Faculty of Medicine and Health Sciences, Medicine and Medical Specialties Department, Universidad de Alcalá, Alcalá de Henares, Spain.
  • Córdoba-Guijarro S; Dermatology Department, Hospital del Mar Research Institute, Universitat Pompeu Fabra, Barcelona, Spain.
  • Sánchez-Pérez J; Dermatology Department, Hospital General Universitario José Mª Morales Meseguer, Murcia, Spain.
  • Silvestre JF; Dermatology Department, Hospital Universitario Infanta Sofía, Madrid, Spain.
  • Frutos FJO; Dermatology Department, Hospital Universitari Germans Trias i Pujol, IGTP, UAB, Barcelona, Spain.
  • Tous-Romero F; Dermatology Department, Hospital Universitario de Fuenlabrada, Madrid, Spain.
  • Fernández-Redondo V; Dermatology Department, Hospital Universitario de La Princesa, Madrid, Spain.
  • Serra-Baldrich E; Dermatology Department, Hospital General Universitario Dr Balmis, ISABIAL, Alicante, Spain.
  • Ruíz-González I; Dermatology Department, Hospital Universitario 12 de Octubre, Madrid, Spain.
  • González Pérez R; Dermatology Department, Hospital Universitario 12 de Octubre, Madrid, Spain.
  • Miquel-Miquel J; Dermatology Department, Complejo Hospitalario Universitario, Santiago de Compostela, Spain.
  • Guillén PS; Dermatology Department, Hospital de La Santa Creu i Sant Pau, Barcelona, Spain.
  • Hervella-García M; Dermatology Department, Complejo Asistencial Universitario de León, León, Spain.
  • Heras-Mendaza F; Dermatology Department, Hospital Universitario De Araba, Vitoria, Spain.
  • Gómez-de-la-Fuente E; Dermatology Department, Hospital Universitario Arnau Vilanova, Valencia, Spain.
  • Zaragoza-Ninet V; Dermatology Department, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain.
  • Gilo AS; Dermatology Department, Complejo Hospitalario de Navarra, Pamplona, Spain.
  • Rodríguez-Serna M; Dermatology Department, Hospital Universitario Fundacion Jiménez Díaz, Madrid, Spain.
  • Melé-Ninot G; Dermatology Department, Hospital Universitario Fundación Alcorcón, Madrid, Spain.
  • Descalzo MÁ; Dermatology Department, Hospital General Universitario de Valencia, Valencia, Spain.
  • de-Vega M; Dermatology Department, Hospital Universitario Rey Juan Carlos, Madrid, Spain.
  • García-Doval I; Dermatology Department, Hospital Universitario La Fe, Valencia, Spain.
  • Borrego L; Dermatology Department, Hospital Universitari Sagrat Cor - Grupo Quirónsalud, Barcelona, Spain.
Contact Dermatitis ; 90(5): 507-513, 2024 May.
Article en En | MEDLINE | ID: mdl-38351475
ABSTRACT

BACKGROUND:

A global epidemic of allergic contact dermatitis to (meth)acrylates has been described in relation to the widespread use of manicure products.

OBJECTIVES:

To evaluate the frequency of sensitization to 2-hydroxyethyl methacrylate (2-HEMA) among consecutively patch tested patients with eczema in Spain; the percentage of current relevance; the MOAHLFA index; and, the potential sources of exposure to (meth)acrylates.

METHODS:

From January 2019 to December 2022, 2-HEMA 2% pet. was prospectively patch tested in 24 REIDAC (Spanish Allergic Contact Dermatitis Registry) centres.

RESULTS:

Six thousand one hundred thirty-four patients were consecutively patch tested with 2-HEMA 2% pet. 265/6134 (4.3%) were positive. Positive reactions of current relevance were identified to involve 184/265 (69%). The efficiency (number of patch tests needed to detect relevant positive patch test reactions) was 34 (6134/184). The variable 'occupational' was found to be significantly associated with a higher risk for relevant positive reactions to 2-HEMA (OR 10.9; 95% CI 8.1-14.9).

CONCLUSION:

(Meth)acrylate sensitization is a prevalent health issue in Spain. 2-HEMA 2% pet. has been identified to be a highly effective (meth)acrylate allergy marker in the GEIDAC baseline series. The responsible authorities should implement policies guaranteeing accurate labelling of industrial, medical, and consumer materials while ensuring the enforcement of said labelling through appropriate legal means.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dermatitis Alérgica por Contacto / Dermatitis Profesional Tipo de estudio: Prognostic_studies Límite: Humans País/Región como asunto: Europa Idioma: En Revista: Contact Dermatitis Año: 2024 Tipo del documento: Article País de afiliación: España Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dermatitis Alérgica por Contacto / Dermatitis Profesional Tipo de estudio: Prognostic_studies Límite: Humans País/Región como asunto: Europa Idioma: En Revista: Contact Dermatitis Año: 2024 Tipo del documento: Article País de afiliación: España Pais de publicación: Reino Unido