Your browser doesn't support javascript.
loading
Diagnostic performance of shear wave measurement in the detection of hepatic fibrosis: A multicenter prospective study.
Kumada, Takashi; Toyoda, Hidenori; Ogawa, Sadanobu; Gotoh, Tatsuya; Yoshida, Yuichi; Yamahira, Masahiro; Hirooka, Masashi; Koizumi, Yohei; Hiasa, Yoichi; Tamai, Tsutomu; Kuromatsu, Ryoko; Matsuzaki, Toshihisa; Suehiro, Tomoyuki; Kamada, Yoshihiro; Sumida, Yoshio; Tanaka, Junko; Shimizu, Masahito.
Afiliación
  • Kumada T; Department of Nursing, Faculty of Nursing, Gifu Kyoritsu University, Ogaki, Japan.
  • Toyoda H; Department of Gastroenterology and Hepatology, Ogaki Municipal Hospital, Ogaki, Japan.
  • Ogawa S; Department of Imaging Diagnosis, Ogaki Municipal Hospital, Ogaki, Japan.
  • Gotoh T; Department of Imaging Diagnosis, Ogaki Municipal Hospital, Ogaki, Japan.
  • Yoshida Y; Department of Gastroenterology and Hepatology, Suita Municipal Hospital, Suita, Japan.
  • Yamahira M; Department of Clinical Laboratory Medicine, Suita Municipal Hospital, Suita, Japan.
  • Hirooka M; Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.
  • Koizumi Y; Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.
  • Hiasa Y; Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.
  • Tamai T; Department of Gastroenterology, Kagoshima City Hospital, Kagoshima, Japan.
  • Kuromatsu R; Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan.
  • Matsuzaki T; Department of Gastroenterology, Sasebo City General Hospital, Sasebo, Japan.
  • Suehiro T; Clinical Research Center, National Hospital Organization Nagasaki Medical Center, Omura, Japan.
  • Kamada Y; Department of Advanced Metabolic Hepatology, Osaka University Graduate School of Medicine, Suita, Japan.
  • Sumida Y; Graduate School of Healthcare Management, International University of Health and Welfare, Minatoku, Tokyo, Japan.
  • Tanaka J; Department of Epidemiology, Infectious Disease Control and Prevention, Hiroshima University Institute of Biomedical and Health Sciences, Hiroshima, Japan.
  • Shimizu M; Department of Gastroenterology/Internal Medicine, Graduate School of Medicine, Gifu University, Gifu, Japan.
Hepatol Res ; 54(9): 851-858, 2024 Sep.
Article en En | MEDLINE | ID: mdl-38349813
ABSTRACT

AIM:

This study aimed to establish the shear wave measurement (SWM) cut-off value for each fibrosis stage using magnetic resonance (MR) elastography values as a reference standard.

METHODS:

We prospectively analyzed 594 patients with chronic liver disease who underwent SWM and MR elastography. Correlation coefficients (were analyzed, and the diagnostic value was evaluated by the area under the receiver operating characteristic curve. Liver stiffness was categorized by MR elastography as F0 (<2.61 kPa), F1 (≥2.61 kPa, <2.97 kPa, any fibrosis), F2 (≥2.97 kPa, <3.62 kPa, significant fibrosis), F3 (≥3.62 kPa, <4.62 kPa, advanced fibrosis), or F4 (≥4.62 kPa, cirrhosis).

RESULTS:

The median SWM values increased significantly with increasing fibrosis stage (p < 0.001). The correlation coefficient between SWM and MR elastography values was 0.793 (95% confidence interval 0.761-0.821). The correlation coefficients between SWM and MR elastography values significantly decreased with increasing body mass index and skin-capsular distance; skin-capsular distance values were associated with significant differences in sensitivity, specificity, accuracy, or positive predictive value, whereas body mass index values were not. The best cut-off values for any fibrosis, significant fibrosis, advanced fibrosis, and cirrhosis were 6.18, 7.09, 8.05, and 10.89 kPa, respectively.

CONCLUSIONS:

This multicenter study in a large number of patients established SWM cut-off values for different degrees of fibrosis in chronic liver diseases using MR elastography as a reference standard. It is expected that these cut-off values will be applied to liver diseases in the future.
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Clinical_trials / Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Hepatol Res Año: 2024 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Clinical_trials / Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Hepatol Res Año: 2024 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Países Bajos