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Natural Compounds in Non-Melanoma Skin Cancer: Prevention and Treatment.
Kowalski, Szymon; Karska, Julia; Tota, Maciej; Skinderowicz, Katarzyna; Kulbacka, Julita; Drag-Zalesinska, Malgorzata.
Afiliación
  • Kowalski S; Faculty of Medicine, Wroclaw Medical University, Pasteura 1, 50-367 Wroclaw, Poland.
  • Karska J; Department of Psychiatry, Wroclaw Medical University, Pasteura 10, 50-367 Wroclaw, Poland.
  • Tota M; Faculty of Medicine, Wroclaw Medical University, Pasteura 1, 50-367 Wroclaw, Poland.
  • Skinderowicz K; Faculty of Medicine, Wroclaw Medical University, Pasteura 1, 50-367 Wroclaw, Poland.
  • Kulbacka J; Department of Molecular and Cellular Biology, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211A, 50-556 Wroclaw, Poland.
  • Drag-Zalesinska M; Department of Immunology and Bioelectrochemistry, State Research Institute Centre for Innovative Medicine, Santariskiu 5, 08410 Vilnius, Lithuania.
Molecules ; 29(3)2024 Feb 04.
Article en En | MEDLINE | ID: mdl-38338469
ABSTRACT
The elevated occurrence of non-melanoma skin cancer (NMSC) and the adverse effects associated with available treatments adversely impact the quality of life in multiple dimensions. In connection with this, there is a necessity for alternative approaches characterized by increased tolerance and lower side effects. Natural compounds could be employed due to their safety profile and effectiveness for inflammatory and neoplastic skin diseases. These anti-cancer drugs are often derived from natural sources such as marine, zoonotic, and botanical origins. Natural compounds should exhibit anti-carcinogenic actions through various pathways, influencing apoptosis potentiation, cell proliferation inhibition, and metastasis suppression. This review provides an overview of natural compounds used in cancer chemotherapies, chemoprevention, and promotion of skin regeneration, including polyphenolic compounds, flavonoids, vitamins, alkaloids, terpenoids, isothiocyanates, cannabinoids, carotenoids, and ceramides.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Antineoplásicos Aspecto: Patient_preference Límite: Humans Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Polonia Pais de publicación: Suiza
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Cutáneas / Antineoplásicos Aspecto: Patient_preference Límite: Humans Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Polonia Pais de publicación: Suiza