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Prostate cancer presentation and management in the Middle East.
Sayan, Mutlay; Langoe, Astrid; Aynaci, Ozlem; Eren, Ayfer Ay; Eren, Mehmet Fuat; Kazaz, Ilke Onur; Ibrahim, Zainab; Al-Akelie, Omar Tama; Al-Mansouri, Loma; Abu-Hijlih, Ramiz; Moningi, Shalini; Abou Chawareb, Elia; El Hajj, Albert; Orio, Peter F; Mula-Hussain, Layth.
Afiliación
  • Sayan M; Brigham and Women's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA. msayan@bwh.harvard.edu.
  • Langoe A; Department of Radiation Oncology, Dana-Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA. msayan@bwh.harvard.edu.
  • Aynaci O; Boston College, Boston, MA, USA.
  • Eren AA; Karadeniz Technical University, Trabzon, Türkiye, Turkey.
  • Eren MF; Kartal Dr. Lütfi Kirdar Education and Research Hospital, Istanbul, Turkey.
  • Kazaz IO; Marmara University, Istanbul Pendik Education and Research Hospital, Istanbul, Türkiye, Turkey.
  • Ibrahim Z; Karadeniz Technical University, Trabzon, Türkiye, Turkey.
  • Al-Akelie OT; King Hamad University Hospital, Al Sayh, Bahrain.
  • Al-Mansouri L; Alamal National Hospital for Cancer Management, Baghdad, Iraq.
  • Abu-Hijlih R; Basrah Medical College, Basra, Iraq.
  • Moningi S; King Hussein Cancer Center, Amman, Jordan.
  • Abou Chawareb E; Brigham and Women's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • El Hajj A; American University of Beirut Medical Center, Beirut, Lebanon.
  • Orio PF; American University of Beirut Medical Center, Beirut, Lebanon.
  • Mula-Hussain L; Brigham and Women's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
BMC Urol ; 24(1): 35, 2024 Feb 09.
Article en En | MEDLINE | ID: mdl-38336732
ABSTRACT

BACKGROUND:

Although prostate cancer is a prevalent malignancy worldwide, its clinical presentation and management in the Middle East are not well-documented. This study aims to provide insights into the initial clinical presentation and management of prostate cancer in this region.

METHODS:

A retrospective review was conducted on seven institutional databases from six Middle Eastern countries, including Türkiye, Lebanon, Iraq, Syria, Bahrain, and Jordan, to identify patients diagnosed with prostate cancer in 2021. Descriptive analysis was performed on the collected data to provide an overview of the demographic, clinical, and treatment variables.

RESULTS:

A total of 1,136 patients were identified with a median age of 70 (range, 50-84). Most patients (78%) received their prostate cancer diagnosis after presenting with symptoms, as opposed to routine PSA screening. At the time of diagnosis, 35% of men had clinical T3 or T4 disease, 54% with Stage IV disease and 50% with Gleason score ≥ 8. Regarding treatment, 20% of non-metastatic and 22% of metastatic patients received no treatment.

CONCLUSION:

Most men in this study sought prostate cancer evaluation due to symptoms and were subsequently diagnosed with advanced-stage disease, providing a foundation for future research aimed at understanding the underlying factors behind the observed trends and enabling informed interventions.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Antígeno Prostático Específico Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans / Male País/Región como asunto: Asia Idioma: En Revista: BMC Urol Asunto de la revista: UROLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
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Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Antígeno Prostático Específico Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans / Male País/Región como asunto: Asia Idioma: En Revista: BMC Urol Asunto de la revista: UROLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido