Your browser doesn't support javascript.
loading
Associations among antimicrobial use, calf management practices, and antimicrobial resistance in Escherichia coli from a pooled fecal sample in calves on Canadian dairy farms: A cross-sectional study.
Uyama, T; Kelton, D F; Morrison, E I; de Jong, E; McCubbin, K D; Barkema, H W; Dufour, S; Fonseca, M; McClure, J T; Sanchez, J; Heider, L C; Renaud, D L.
Afiliación
  • Uyama T; Department of Population Medicine, University of Guelph, Guelph, ON, N1G 2W1, Canada.
  • Kelton DF; Department of Population Medicine, University of Guelph, Guelph, ON, N1G 2W1, Canada.
  • Morrison EI; Department of Population Medicine, University of Guelph, Guelph, ON, N1G 2W1, Canada.
  • de Jong E; Faculty of Veterinary Medicine, University of Calgary, Calgary, AB, T2N 4N1, Canada.
  • McCubbin KD; Faculty of Veterinary Medicine, University of Calgary, Calgary, AB, T2N 4N1, Canada.
  • Barkema HW; Faculty of Veterinary Medicine, University of Calgary, Calgary, AB, T2N 4N1, Canada.
  • Dufour S; Faculté de Médecine Vétérinaire, Université de Montréal, St-Hyacinthe, QC, J2S 2M2, Canada.
  • Fonseca M; Department of Health Management, Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, PE, C1A 4P3, Canada.
  • McClure JT; Department of Health Management, Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, PE, C1A 4P3, Canada.
  • Sanchez J; Department of Health Management, Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, PE, C1A 4P3, Canada.
  • Heider LC; Department of Health Management, Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, PE, C1A 4P3, Canada.
  • Renaud DL; Department of Population Medicine, University of Guelph, Guelph, ON, N1G 2W1, Canada. Electronic address: renaudd@uoguelph.ca.
J Dairy Sci ; 107(7): 4961-4972, 2024 Jul.
Article en En | MEDLINE | ID: mdl-38331174
ABSTRACT
The objective of this cross-sectional study was to determine associations between calf management practices, the number of antimicrobial treatments, and antimicrobial resistance in preweaning heifers on Canadian dairy farms. A composite of 5 fecal samples from preweaning calves was collected from 142 dairy farms in 5 provinces and analyzed for phenotypic antimicrobial susceptibility with the microbroth dilution method. Questionnaires were used to capture herd characteristics and calf management practices used on the farm. Calf treatment records were collected during the farm visits. Escherichia coli was isolated from all 142 fecal samples with the highest resistance to tetracycline (41%), followed by sulfisoxazole (36%), streptomycin (32%), chloramphenicol (28%), ampicillin (16%), trimethoprim-sulfamethoxazole (15%), ceftriaxone (4.2%), cefoxitin (2.8%), amoxicillin-clavulanic acid (2.1%), ciprofloxacin (2.1%), nalidixic acid (2.1%), azithromycin (1.4%), and gentamicin (1.4%). Multidrug resistance was observed in 37% of E. coli isolates. Three-quarters of farms used fresh colostrum as the most common type of colostrum fed to calves. Colostrum quality was checked on 49% of farms, but the transfer of passive immunity was only checked on 32% of farms in the last 12 mo. Almost 70% of farms used straw or hay or a combination as the bedding material for calves. Among the 142 farms, a complete set of calf records were collected from 71 farms. In a multivariable logistic regression model, farms with ≥1.99 to 32.57 antimicrobial treatments/calf-year were 3.2 times more likely to have multidrug resistant E. coli in calf feces compared farms with <1.99 antimicrobial treatments/calf-year. Farms using hay or straw beddings were 5.1 times less likely to have multidrug resistant E. coli compared with those with other bedding materials including shavings or sawdust. Bedding management practices on farms may need to be investigated to reduce the potential effect on disseminating multidrug resistant bacteria.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Escherichia coli / Heces Tipo de estudio: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Animals País/Región como asunto: America do norte Idioma: En Revista: J Dairy Sci Año: 2024 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Escherichia coli / Heces Tipo de estudio: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Animals País/Región como asunto: America do norte Idioma: En Revista: J Dairy Sci Año: 2024 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Estados Unidos