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Association of milk microbiome with bovine mastitis before and after antibiotic therapy.
Burakova, Inna; Gryaznova, Mariya; Smirnova, Yuliya; Morozova, Polina; Mikhalev, Vitaliy; Zimnikov, Vitaliy; Latsigina, Irina; Shabunin, Sergey; Mikhailov, Evgeny; Syromyatnikov, Mikhail.
Afiliación
  • Burakova I; Laboratory of Metagenomics and Food Biotechnology, Voronezh State University of Engineering Technologies, 394036 Voronezh, Russia.
  • Gryaznova M; Laboratory of Metagenomics and Food Biotechnology, Voronezh State University of Engineering Technologies, 394036 Voronezh, Russia.
  • Smirnova Y; Laboratory of Metagenomics and Food Biotechnology, Voronezh State University of Engineering Technologies, 394036 Voronezh, Russia.
  • Morozova P; Laboratory of Metagenomics and Food Biotechnology, Voronezh State University of Engineering Technologies, 394036 Voronezh, Russia.
  • Mikhalev V; Department of Genetics, Cytology and Bioengineering, Voronezh State University, 394018 Voronezh, Russia.
  • Zimnikov V; FSBSI All-Russian Veterinary Research Institute of Pathology, Pharmacology and Therapy, 394061 Voronezh, Russia.
  • Latsigina I; FSBSI All-Russian Veterinary Research Institute of Pathology, Pharmacology and Therapy, 394061 Voronezh, Russia.
  • Shabunin S; FSBSI All-Russian Veterinary Research Institute of Pathology, Pharmacology and Therapy, 394061 Voronezh, Russia.
  • Mikhailov E; FSBSI All-Russian Veterinary Research Institute of Pathology, Pharmacology and Therapy, 394061 Voronezh, Russia.
  • Syromyatnikov M; FSBSI All-Russian Veterinary Research Institute of Pathology, Pharmacology and Therapy, 394061 Voronezh, Russia.
Vet World ; 16(12): 2389-2402, 2023 Dec.
Article en En | MEDLINE | ID: mdl-38328355
ABSTRACT
Background and

Aim:

Mastitis is recognized as the most common disease in cattle and causes economic losses in the dairy industry. A number of opportunistic bacterial taxa have been identified as causative agents for this disease. Conventionally, antibiotics are used to treat mastitis; however, most bacteria are resistant to the majority of antibiotics. This study aimed to use molecular methods to identify milk microbiome patterns characteristic of mastitis that can help in the early diagnosis of this disease and in the development of new treatment strategies. Materials and

Methods:

To evaluate the microbiome composition, we performed NGS sequencing of the 16S rRNA gene of the V3 region.

Results:

An increase in the abundance of the bacterial genera Hymenobacter and Lachnospiraceae NK4A136 group is associated with the development of subclinical and clinical mastitis in dairy cows. These bacteria can be added to the list of markers used to detect mastitis in cows. Furthermore, a decrease in the abundance of Ralstonia, Lachnospiraceae NK3A20 group, Acetitomaculum, Massilia, and Atopostipes in cows with mastitis may indicate their role in maintaining a healthy milk microbiome. Antibiotics reduced the levels of Streptococcus in milk compared to those in the healthy group and cows before antibiotic treatment. Antibiotic therapy also contributed to an increase in the abundance of beneficial bacteria of the genus Asticcacaulis.

Conclusion:

This study expands our understanding of the association between milk microbiota and mastitis.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies / Risk_factors_studies / Screening_studies Idioma: En Revista: Vet World Año: 2023 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: India
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies / Risk_factors_studies / Screening_studies Idioma: En Revista: Vet World Año: 2023 Tipo del documento: Article País de afiliación: Rusia Pais de publicación: India