Targeted Therapies for Neonatal Pulmonary Hypertension: Beyond Nitric Oxide.

Carroll, Jeanne; Rao, Rohit; Steinhorn, Robin H

Carroll, Jeanne; Rao, Rohit; Steinhorn, Robin H.

Afiliación

Carroll J; Division of Neonatology, Department of Pediatrics, University of California, San Diego, Rady Children's Hospital-San Diego, 3030 Children's Way, San Diego, CA 92123, USA.
Rao R; Division of Cardiothoracic Critical Care, Department of Pediatrics, University of California, San Diego, Rady Children's Hospital-San Diego, 3030 Children's Way, San Diego, CA 92123, USA.
Steinhorn RH; Department of Pediatrics, University of California, San Diego, Rady Children's Hospital-San Diego, 3020 Children's Way, San Diego, CA 92123, USA. Electronic address: rsteinhorn@rchsd.org.

Clin Perinatol ; 51(1): 113-126, 2024 03.

Article en En | MEDLINE | ID: mdl-38325937

ABSTRACT

ABSTRACT

Pulmonary hypertension in the neonatal population can be acute or chronic and carries significant risk for morbidity and mortality. It can be idiopathic but more often is associated with comorbid pulmonary and heart disease. There are several pharmacotherapeutics aimed at pulmonary vasodilation. This review highlights the most common agents as well as those on the horizon for the treatment of pulmonary hypertension in the neonate.

Asunto(s)

Hipertensión Pulmonar; Óxido Nítrico; Recién Nacido; Humanos; Óxido Nítrico/uso terapéutico; Hipertensión Pulmonar/tratamiento farmacológico; Vasodilatación; Pulmón; Administración por Inhalación

Palabras clave

Endothelin; Phosphodiesterase; Prostacyclin; Pulmonary hypertension; Pulmonary vasculature

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hipertensión Pulmonar / Óxido Nítrico Límite: Humans / Newborn Idioma: En Revista: Clin Perinatol Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

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