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Ultrabright Green-Emissive Nanodots for Precise Biological Visualization.
Guo, Yuxin; Wang, Zihao; Chen, Yu; Chao, Furong; Xu, Yin; Qu, Lu-Lu; Wu, Fu-Gen; Dong, Xiaochen.
Afiliación
  • Guo Y; School of Chemistry & Materials Science, Jiangsu Normal University, 101 Shanghai Road, Xuzhou 221116, China.
  • Wang Z; State Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, Southeast University, 2 Sipailou Road, Nanjing 210096, China.
  • Chen Y; School of Chemistry & Materials Science, Jiangsu Normal University, 101 Shanghai Road, Xuzhou 221116, China.
  • Chao F; School of Chemistry & Materials Science, Jiangsu Normal University, 101 Shanghai Road, Xuzhou 221116, China.
  • Xu Y; School of Chemistry & Materials Science, Jiangsu Normal University, 101 Shanghai Road, Xuzhou 221116, China.
  • Qu LL; School of Chemistry & Materials Science, Jiangsu Normal University, 101 Shanghai Road, Xuzhou 221116, China.
  • Wu FG; State Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, Southeast University, 2 Sipailou Road, Nanjing 210096, China.
  • Dong X; School of Chemistry & Materials Science, Jiangsu Normal University, 101 Shanghai Road, Xuzhou 221116, China.
Nano Lett ; 24(7): 2264-2272, 2024 Feb 21.
Article en En | MEDLINE | ID: mdl-38324803
ABSTRACT
Developing general methods to fabricate water-dispersible and biocompatible fluorescent probes will promote different biological visualization applications. Herein, we report a metal-facilitated method to fabricate ultrabright green-emissive nanodots via the one-step solvothermal treatment of rose bengal, ethanol, and various metal ions. These metal-doped nanodots show good water dispersity, ultrahigh photoluminescence quantum yields (PLQYs) (e.g., the PLQY of Fe-doped nanodots (FeNDs) was ∼97%), and low phototoxicity. Owing to the coordination effect of metal ions, the FeNDs realize glutathione detection with outstanding properties. Benefiting from the high endoplasmic reticulum (ER) affinity of the chloride group, the FeNDs can act as an ER tracker with long ER imaging capacity (FeNDs >24 h; commercial ER tracker ∼1 h) and superb photostability and can achieve tissue visualization in living Caenorhabditis elegans. The metal-doped nanodots represent a general nanodot preparation method and may shed new light on diverse biological visualization uses.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Puntos Cuánticos Idioma: En Revista: Nano Lett Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Puntos Cuánticos Idioma: En Revista: Nano Lett Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos