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Nonsteroidal Approaches for Atopic Dermatitis: A Clinical Update.
Ch'en, Peter Y; Lio, Peter A.
Afiliación
  • Ch'en PY; From the Division of Dermatology, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA.
  • Lio PA; Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Dermatitis ; 2024 Feb 06.
Article en En | MEDLINE | ID: mdl-38320243
ABSTRACT
Topical corticosteroids (TCSs) are the most widely used treatment for atopic dermatitis (AD), but they can have adverse effects such as skin atrophy, telangiectasias, and hypopigmentation, especially with prolonged use of higher potency steroids. Many patients also have a fear of using TCSs, known as "corticophobia." With the development of biologics and Janus kinase inhibitors, a nonsteroidal approach to the treatment of AD may be possible and may be preferred by certain patients. Given what is known about these nonsteroidal therapies, we propose a structured treatment ladder and action plan that can guide clinicians and patients on the use of these therapies for the treatment of AD. The ladder divides nonsteroidal medication classes into treatments for exacerbation versus maintenance therapies in an escalating order of increasing potential for adverse effects, both real and perceived. This treatment algorithm proposal paves the way for a potential nonsteroidal approach to managing AD.

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Dermatitis Asunto de la revista: DERMATOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Dermatitis Asunto de la revista: DERMATOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos