Targeted Therapy for the Predominant Form of Mastocytosis.
NEJM Evid
; 2(6): EVIDe2300089, 2023 Jun.
Article
en En
| MEDLINE
| ID: mdl-38320134
ABSTRACT
Mast cells are present in all vascularized tissues, often associated with blood vessels, glandular structures, and nerves, and they tend to be more numerous in tissues that interface with the external environment, including the skin and gastrointestinal tract. These mast cells are involved in both innate and acquired immunity, as well as in other biologic processes, including wound healing. Mast cell numbers within tissues are remarkably consistent, although mast cell numbers somewhat increase in association with inflammation. Human mast cells have two principal receptors that when stimulated, lead to cellular activation.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Mastocitosis
Límite:
Humans
Idioma:
En
Revista:
NEJM Evid
Año:
2023
Tipo del documento:
Article
País de afiliación:
Moldova
Pais de publicación:
Estados Unidos