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The value of the first postoperative diagnostic I-131 scan in patients with papillary thyroid carcinoma.
Ran, Bingyu; Shang, Jingjie; Chen, Yong; Zhou, Miaoli; Li, Huihu; He, Wenjun; Li, Yingxin; Cai, Qijun; Guo, Bin; Gong, Jian; Xu, Hao.
Afiliación
  • Ran B; Department of Nuclear Medicine, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong Province, China.
  • Shang J; Department of Nuclear Medicine, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong Province, China.
  • Chen Y; Department of Nuclear Medicine, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong Province, China.
  • Zhou M; Department of Nuclear Medicine, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong Province, China.
  • Li H; Department of Nuclear Medicine, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong Province, China.
  • He W; Department of Nuclear Medicine, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong Province, China.
  • Li Y; Department of Nuclear Medicine, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong Province, China.
  • Cai Q; Department of Nuclear Medicine, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong Province, China.
  • Guo B; Department of Nuclear Medicine, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong Province, China.
  • Gong J; Department of Nuclear Medicine, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong Province, China. gongjian2021@163.com.
  • Xu H; Department of Nuclear Medicine, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong Province, China. txh@jnu.edu.cn.
J Cancer Res Clin Oncol ; 150(2): 80, 2024 Feb 06.
Article en En | MEDLINE | ID: mdl-38319395
ABSTRACT

OBJECTIVE:

To explore the feasibility of the postoperative diagnostic 131I whole-body planar scans (Dx-WBS) in papillary thyroid cancer (PTC) patients, and to clarify its value for accurate staging, risk stratification, and postoperative radioactive iodine (RAI) treatment management.

DESIGN:

Retrospective study from 2015 to 2021.

SETTING:

A total of 1294 PTC patients in the tertiary referral hospital.

PARTICIPANTS:

Patients with differentiated thyroid cancer who underwent total/subtotal thyroidectomy were included. Patients with non-PTC pathological type, non-first RAI treatment, and incomplete data such as Dx-WBS and postablation WBS (Rx-WBS) were excluded.

METHODS:

The diagnostic efficacy of Dx-WBS was calculated with Rx-WBS as the reference. All patients were initially staged by the 8th edition of TNM staging, and risk stratification was performed based on clinical and pathological information. After Dx-WBS, the risk stratification was re-evaluated, and management was reconfirmed.

RESULTS:

The detection rates of Dx-WBS for residual thyroid, cervical lymph nodes, upper mediastinal lymph nodes, lung, and bone distant metastasis were 97.6%, 78.3%, 82.1%, 66.7%, and 61.2%, respectively. The risk stratification of 113 patients (8.7%) changed after Dx-WBS, of which 107 patients changed from low to intermediate risk, 2 from low to high risk, and 4 from medium to high risk. A total of 241 patients (18.6%) adjusted the RAI regimen after Dx-WBS.

CONCLUSION:

This study confirms the diagnostic efficacy of the postoperative Dx-WBS in PTC patients and the value of Dx-WBS in accurately assessing risk stratification, as well as assisting in determining RAI treatment.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Tiroides / Radioisótopos de Yodo Tipo de estudio: Diagnostic_studies / Observational_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: J Cancer Res Clin Oncol Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Tiroides / Radioisótopos de Yodo Tipo de estudio: Diagnostic_studies / Observational_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: J Cancer Res Clin Oncol Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Alemania