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Systematic review of the use of ultrasound for venous assessment and venous thrombosis screening in spaceflight.
Elias, Antoine; Weber, Tobias; Green, David A; Harris, Katie M; Laws, Jonathan M; Greaves, Danielle K; Kim, David S; Mazzolai-Duchosal, Lucia; Roberts, Lara; Petersen, Lonnie G; Limper, Ulrich; Bergauer, Andrej; Elias, Michael; Winnard, Andrew; Goswami, Nandu.
Afiliación
  • Elias A; Cardiology and Vascular Medicine, Sainte Musse Hospital, Toulon Hospital Centre, Toulon, France. antoinelias@gmail.com.
  • Weber T; Clinical Research and Innovation, Sainte Musse Hospital, Toulon Hospital Centre, Toulon, France. antoinelias@gmail.com.
  • Green DA; Investigation Network On Venous Thrombo-Embolism | French Clinical Research Infrastructure Network (INNOVTE | F-CRIN), Toulon, France. antoinelias@gmail.com.
  • Harris KM; Space Medicine Team (HRE-OM), European Astronaut Center (EAC), European Space Agency (ESA), Cologne, Germany.
  • Laws JM; KBR, Cologne, Germany.
  • Greaves DK; Space Medicine Team (HRE-OM), European Astronaut Center (EAC), European Space Agency (ESA), Cologne, Germany.
  • Kim DS; KBR, Cologne, Germany.
  • Mazzolai-Duchosal L; Centre of Human and Applied Physiological Sciences, King's College London, London, United Kingdom.
  • Roberts L; Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL, Canada.
  • Petersen LG; University of Northumbria at Newcastle, Newcaslte-upon-Tyne, United Kingdom.
  • Limper U; Space Biomedicine Systematic Review Methods Group, Wylam, United Kingdom.
  • Bergauer A; Faculty of Health, University of Waterloo, Waterloo, ON, Canada.
  • Elias M; Space Medicine Team (HRE-OM), European Astronaut Center (EAC), European Space Agency (ESA), Cologne, Germany.
  • Winnard A; Department of Emergency Medicine, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.
  • Goswami N; Department of Angiology, Lausanne University, Lausanne, Switzerland.
NPJ Microgravity ; 10(1): 14, 2024 Feb 05.
Article en En | MEDLINE | ID: mdl-38316814
ABSTRACT
The validity of venous ultrasound (V-US) for the diagnosis of deep vein thrombosis (DVT) during spaceflight is unknown and difficult to establish in diagnostic accuracy and diagnostic management studies in this context. We performed a systematic review of the use of V-US in the upper-body venous system in spaceflight to identify microgravity-related changes and the effect of venous interventions to reverse them, and to assess appropriateness of spaceflight V-US with terrestrial standards. An appropriateness tool was developed following expert panel discussions and review of terrestrial diagnostic studies, including criteria relevant to crew experience, in-flight equipment, assessment sites, ultrasound modalities, and DVT diagnosis. Microgravity-related findings reported as an increase in internal jugular vein (IJV) cross-sectional area and pressure were associated with reduced, stagnant, and retrograde flow. Changes were on average responsive to venous interventions using lower body negative pressure, Bracelets, Valsalva and Mueller manoeuvres, and contralateral IJV compression. In comparison with terrestrial standards, spaceflight V-US did not meet all appropriateness criteria. In DVT studies (n = 3), a single thrombosis was reported and only ultrasound modality criterion met the standards. In the other studies (n = 15), all the criteria were appropriate except crew experience criterion, which was appropriate in only four studies. Future practice and research should account for microgravity-related changes, evaluate individual effect of venous interventions, and adopt Earth-based V-US standards.

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies / Guideline / Prognostic_studies / Screening_studies / Systematic_reviews Idioma: En Revista: NPJ Microgravity Año: 2024 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies / Guideline / Prognostic_studies / Screening_studies / Systematic_reviews Idioma: En Revista: NPJ Microgravity Año: 2024 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Estados Unidos