Making sense of the costs of adversity throughout the lifespan on aging in humans and other animals.
Neurosci Biobehav Rev
; 159: 105571, 2024 Apr.
Article
en En
| MEDLINE
| ID: mdl-38316195
ABSTRACT
Social adversity, particularly early in life, can cause lifelong damage to health; by now, numerous studies examine this relationship in non-human species, producing some important themes A) Captive animals readily lack ethological validity, giving a special place to studies of natural populations; one must appreciate though, that animal studies typically benefit humans who themselves lack ecological validity, namely Westernized subjects. B) Animal studies of the links between social adversity and psychiatric maladies potentially produce anthropomorphism; however, long-term study of our closest relatives demonstrates how convincingly another primate can, for example, experience grief, rather than display "grief-like" behavior. C) Are long-term consequences of social adversity best viewed as maladaptive and pathological, or as adaptive preparation for similar adversity later in life?; the growing literature casts light on when adversity's consequences are the purview of medicine or natural history. D) Studies examining sustained adversity and aging can increasingly distinguish between aging versus diseases of aging or cohort effects, and between aging effects arising from direct physiological mechanisms or indirect behavioral ones.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Envejecimiento
/
Longevidad
Tipo de estudio:
Health_economic_evaluation
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Neurosci Biobehav Rev
Año:
2024
Tipo del documento:
Article
Pais de publicación:
Estados Unidos