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Invasive fungal rhinosinusitis by Fusarium proliferatum/annulatum in a patient with acute myeloid leukemia: A case report and review of the literature.
Caliskan, Zeynep Cansu; Karahan, Gizem; Koray, Neslihan; Gokcinar, Yasin; Gülmez, Dolunay; Arikan-Akdagli, Sevtap; Unal, Serhat; Uzun, Omrum.
Afiliación
  • Caliskan ZC; Hacettepe University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Ankara, Turkey. Electronic address: zeynepcansuduran@hacettepe.edu.tr.
  • Karahan G; Hacettepe University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Ankara, Turkey.
  • Koray N; Hacettepe University Faculty of Medicine, Department of Internal Medicine, Ankara, Turkey.
  • Gokcinar Y; Hacettepe University Faculty of Medicine, Department of Otorhinolaryngology, Ankara, Turkey.
  • Gülmez D; Hacettepe University Faculty of Medicine, Department of Medical Microbiology, Ankara, Turkey.
  • Arikan-Akdagli S; Hacettepe University Faculty of Medicine, Department of Medical Microbiology, Ankara, Turkey.
  • Unal S; Hacettepe University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Ankara, Turkey.
  • Uzun O; Hacettepe University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Ankara, Turkey.
J Mycol Med ; 34(1): 101461, 2024 Mar.
Article en En | MEDLINE | ID: mdl-38310659
ABSTRACT
Antifungal prophylaxis with a mold-effective agent has led to a substantial decrease in invasive infections caused by Aspergillus spp. in the management of patients with acute myeloid leukemia undergoing induction chemotherapy. However, difficult-to-treat infections caused by other molds, such as Fusarium, Lomentospora, and Scedosporium species may still complicate the neutropenic period. Here, we present a case of a 23-year-old woman with acute myeloid leukemia who developed a breakthrough invasive fungal rhinosinusitis caused by Fusarium proliferatum/annulatum on posaconazole prophylaxis. The infection was diagnosed using clinical, microbiological, and radiological criteria and the isolate was identified using Matrix Assisted Lazer Desorption Ionization Time of Flight Mass Spectrometry (MALDI-TOF MS) and sequencing. We searched Pubmed with "Fusarium proliferatum", "Fusarium annulatum", "immunosuppression AND fusariosis", "rhinosinusitis AND Fusarium proliferatum" and summarized the English literature for similar rhinosinusitis cases infected with the same pathogen.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda / Fusariosis / Fusarium / Rinosinusitis Tipo de estudio: Prognostic_studies Límite: Adult / Female / Humans Idioma: En Revista: J Mycol Med Año: 2024 Tipo del documento: Article Pais de publicación: Francia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda / Fusariosis / Fusarium / Rinosinusitis Tipo de estudio: Prognostic_studies Límite: Adult / Female / Humans Idioma: En Revista: J Mycol Med Año: 2024 Tipo del documento: Article Pais de publicación: Francia