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Reconfiguring a Plane-Parallel Transmission Ionization Chamber to Extend the Operating Range into the Ultra-High Dose-per-pulse Regime.
Konradsson, Elise; Ericsson Szecsenyi, Rebecka; Wahlqvist, Pontus; Thoft, Andreas; Blad, Börje; Bäck, Sven Åj; Ceberg, Crister; Petersson, Kristoffer.
Afiliación
  • Konradsson E; Medical Radiation Physics, Department of Clinical Sciences, Lund University, Lund, Sweden.
  • Ericsson Szecsenyi R; Medical Radiation Physics, Department of Clinical Sciences, Lund University, Lund, Sweden.
  • Wahlqvist P; Radiation Physics, Department of Hematology, Oncology and Radiation Physics, Skåne University Hospital, Lund, Sweden.
  • Thoft A; Radiation Physics, Department of Hematology, Oncology and Radiation Physics, Skåne University Hospital, Lund, Sweden.
  • Blad B; Medical Radiation Physics, Department of Clinical Sciences, Lund University, Lund, Sweden.
  • Bäck SÅ; Radiation Physics, Department of Hematology, Oncology and Radiation Physics, Skåne University Hospital, Lund, Sweden.
  • Ceberg C; Medical Radiation Physics, Department of Clinical Sciences, Lund University, Lund, Sweden.
  • Petersson K; Radiation Physics, Department of Hematology, Oncology and Radiation Physics, Skåne University Hospital, Lund, Sweden.
Radiat Res ; 201(3): 252-260, 2024 03 01.
Article en En | MEDLINE | ID: mdl-38308528
ABSTRACT
This study aims to investigate the feasibility of enhancing the charge collection efficiency (CCE) of a transmission chamber by reconfiguring its design and operation. The goal was to extend the range of dose-per-pulse (DPP) values with no or minimal recombination effects up to the ultra-high dose rate (UHDR) regime. The response of two transmission chambers, with electrode distance of 1 mm and 0.6 mm, respectively, was investigated as a function of applied voltage. The chambers were mounted one-by-one in the electron applicator of a 10 MeV FLASH-modified clinical linear accelerator. The chamber signals were measured as a function of nominal DPP, which was determined at the depth of dose maximum using EBT-XD film in solid water and ranged from 0.6 mGy per pulse to 0.9 Gy per pulse, for both the standard voltage of 320 V and the highest possible safe voltage of 1,200 V. The CCE was calculated and fitted with an empirical logistic function that incorporated the electrode distance and the chamber voltage. The CCE decreased with increased DPP. The CCE at the highest achievable DPP was 24% (36%) at 320 V and 51% (82%) at 1,200 V, for chambers with 1 mm (0.6 mm) electrode distance. For the combination of 1,200 V- and 0.6-mm electrode distance, the CCE was ∼100% for average dose rate up to 70 Gy/s at the depth of dose maximum in the phantom at a source-to-surface distance of 100 cm. Our findings indicate that minor modifications to a plane-parallel transmission chamber can substantially enhance the CCE and extending the chamber's operating range to the UHDR regime. This supports the potential of using transmission chamber-based monitoring solutions for UHDR beams, which could facilitate the delivery of UHDR treatments using an approach similar to conventional clinical delivery.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aceleradores de Partículas / Radiometría Idioma: En Revista: Radiat Res Año: 2024 Tipo del documento: Article País de afiliación: Suecia Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aceleradores de Partículas / Radiometría Idioma: En Revista: Radiat Res Año: 2024 Tipo del documento: Article País de afiliación: Suecia Pais de publicación: Estados Unidos