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Analysis of clinical characteristics and factors influencing herpes simplex virus keratitis.
Zhang, Shuai; Mi, Jinhua; Ge, Shengmei; Wang, Guoqiang; Zhou, Zhongyou; Zhao, Yantao; Zhao, Yan.
Afiliación
  • Zhang S; Department of Ophthalmology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
  • Mi J; Department of Ophthalmology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
  • Ge S; Intensive Care Medicine, The Forth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
  • Wang G; Department of Ophthalmology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
  • Zhou Z; Department of Ophthalmology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
  • Zhao Y; Department of Ophthalmology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
  • Zhao Y; Department of Ophthalmology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Front Med (Lausanne) ; 10: 1267783, 2023.
Article en En | MEDLINE | ID: mdl-38293295
ABSTRACT

Objective:

To investigate the clinical characteristics and factors associated with herpes simplex virus keratitis.

Methods:

Patients with herpes simplex virus keratitis who came to our hospital from January 2018 to June 2022 were selected and divided into a good prognosis group and a poor prognosis group according to their prognosis. The clinical data of the two groups were compared, and univariate/multivariate logistic regression was used to analyze the factors influencing the poor prognosis of herpes simplex virus keratitis.

Results:

A one-way analysis of variance showed that, compared with the good prognosis group, the poor prognosis group had more elderly patients and a longer course of disease, and the difference was statistically significant (p < 0.05). There were significant differences in the types of patients between the two groups (p < 0.05). Univariate logistic regression analysis also showed that age (≥65 years) (OR 1.557, 95%CI 1.081-2.183, p < 0.05), course of disease (> 7 months) (OR 1.303, 95%CI 1.003-1.829, p < 0.05), epithelial type (OR 2.321, 95%CI 1.198-4.321, p < 0.05), and stromal type (OR 2.536, 95%CI 1.672-3.871, p < 0.05) were risk factors for poor prognosis. Multivariate logistic regression analysis showed that age (≥65 years) (OR 1.656, 95%CI 1.168-2.357, p < 0.05) and course of disease (> 7 months) (OR 1.461, 95%CI 1.031-2.001, p < 0.05) were independent risk factors for the prognosis of herpes simplex keratitis.

Conclusion:

The clinical symptoms of herpes simplex virus keratitis include corneal opacity, corneal posterior elastic layer folds, corneal infiltration, posterior corneal mass, corneal edema, and ocular pain. Age and course of disease are important factors in the prognosis of herpes simplex virus keratitis.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Front Med (Lausanne) Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Front Med (Lausanne) Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza