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Factors influencing the development of infantile traumatic brain injury with a biphasic clinical course and late reduced diffusion.
Yasukohchi, Madoka; Omata, Taku; Ochiai, Kenta; Sano, Kentaro; Murofushi, Yuka; Kimura, Sho; Takase, Nanako; Honda, Takafumi; Yasukawa, Kumi; Takanashi, Jun-Ichi.
Afiliación
  • Yasukohchi M; Department of Pediatrics, Tokyo Women's Medical University Yachiyo Medical Center, 477-96 Owadashinden, Yachiyo-shi, Chiba 276-8524, Japan. Electronic address: yasukohchi.madoka@twmu.ac.jp.
  • Omata T; Department of Pediatrics, Tokyo Women's Medical University Yachiyo Medical Center, 477-96 Owadashinden, Yachiyo-shi, Chiba 276-8524, Japan. Electronic address: takuoma@hotmail.co.jp.
  • Ochiai K; Department of Pediatrics, Tokyo Women's Medical University Yachiyo Medical Center, 477-96 Owadashinden, Yachiyo-shi, Chiba 276-8524, Japan.
  • Sano K; Department of Pediatrics, Tokyo Women's Medical University Yachiyo Medical Center, 477-96 Owadashinden, Yachiyo-shi, Chiba 276-8524, Japan.
  • Murofushi Y; Department of Pediatrics, Tokyo Women's Medical University Yachiyo Medical Center, 477-96 Owadashinden, Yachiyo-shi, Chiba 276-8524, Japan.
  • Kimura S; Department of Pediatric Critical Care Medicine, Tokyo Women's Medical University Yachiyo Medical Center, 477-96 Owadashinden, Yachiyo-shi, Chiba 276-8524, Japan.
  • Takase N; Department of Pediatrics, Tokyo Women's Medical University Yachiyo Medical Center, 477-96 Owadashinden, Yachiyo-shi, Chiba 276-8524, Japan.
  • Honda T; Department of Pediatric Critical Care Medicine, Tokyo Women's Medical University Yachiyo Medical Center, 477-96 Owadashinden, Yachiyo-shi, Chiba 276-8524, Japan. Electronic address: honda3@df6.so-net.ne.jp.
  • Yasukawa K; Department of Pediatric Critical Care Medicine, Tokyo Women's Medical University Yachiyo Medical Center, 477-96 Owadashinden, Yachiyo-shi, Chiba 276-8524, Japan. Electronic address: kumi.y@nifty.com.
  • Takanashi JI; Department of Pediatrics, Tokyo Women's Medical University Yachiyo Medical Center, 477-96 Owadashinden, Yachiyo-shi, Chiba 276-8524, Japan. Electronic address: jtaka@twmu.ac.jp.
J Neurol Sci ; 457: 122904, 2024 Feb 15.
Article en En | MEDLINE | ID: mdl-38290378
ABSTRACT

BACKGROUND:

Infantile traumatic brain injury (TBI) with a biphasic clinical course and late reduced diffusion (TBIRD) has been reported as a type of TBI. However, it remains uncertain which pediatric patients with TBI develop TBIRD.

METHODS:

Patients with TBI who were admitted to our hospital and underwent magnetic resonance imaging (MRI) between December 2006 and October 2022 were included in this study. A diagnosis of TBIRD was made in patients with or suspected TBI, with initial symptoms being convulsions or disturbance of consciousness and late-onset subcortical reduced diffusion, the so-called bright tree appearance. Clinical features, neuroimaging (computed tomography (CT) and MRI) findings, laboratory data, and Tada score were retrospectively compared between TBIRD and non-TBIRD patients. Neurological prognosis was assessed using the Pediatric Cerebral Performance Category scale.

RESULTS:

Of 21 patients who met the inclusion criteria, a diagnosis of TBIRD was made in 7 patients (median age 8 months). The factors contributing to TBIRD development were seizures lasting over 30 min as the initial symptom (5/7 in TBIRD vs. 0/14 in non-TBIRD), tracheal intubation during initial treatment (5/7 vs. 0/14), and brain parenchymal lesions on CT (3/7 vs. 0/14), suggesting that severe TBI may progress to TBIRD. The Tada score was more positive in patients with TBIRD (6/7) than in those without (0/14).

CONCLUSIONS:

It is important to monitor infant patients with severe TBI for the development of TBIRD. The Tada score can be a useful tool for TBIRD prediction.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Convulsiones / Lesiones Traumáticas del Encéfalo Tipo de estudio: Prognostic_studies Límite: Child / Humans / Infant Idioma: En Revista: J Neurol Sci Año: 2024 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Convulsiones / Lesiones Traumáticas del Encéfalo Tipo de estudio: Prognostic_studies Límite: Child / Humans / Infant Idioma: En Revista: J Neurol Sci Año: 2024 Tipo del documento: Article Pais de publicación: Países Bajos