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Association between laughter, frailty, and depression in rheumatoid arthritis patients.
Suzuki, Mochihito; Kojima, Toshihisa; Terabe, Kenya; Ohashi, Yoshifumi; Sato, Ryo; Kosugiyama, Hironobu; Hasegawa, Junya; Ohno, Yusuke; Nagai, Kaoru; Ohnishi, Chinami; Sugiura, Hideshi; Fujita, Hitomi; Nagayoshi, Mako; Kojima, Masayo; Asai, Shuji; Imagama, Shiro.
Afiliación
  • Suzuki M; Department of Orthopedic Surgery and Rheumatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Kojima T; Department of Orthopedic Surgery and Rheumatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Terabe K; Department of Orthopedic Surgery, National Hospital Organization, Nagoya Medical Center, Nagoya, Japan.
  • Ohashi Y; Department of Orthopedic Surgery and Rheumatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Sato R; Department of Orthopedic Surgery and Rheumatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Kosugiyama H; Department of Orthopedic Surgery and Rheumatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Hasegawa J; Department of Orthopedic Surgery and Rheumatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Ohno Y; Department of Orthopedic Surgery and Rheumatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Nagai K; Department of Orthopedic Surgery and Rheumatology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Ohnishi C; Nagoya Garden Clinic, Nagoya, Japan.
  • Sugiura H; Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Fujita H; Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Nagayoshi M; Faculty of Health Sciences, Department of Rehabilitation, Nihon Fukushi University, Handa, Japan.
  • Kojima M; Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Asai S; Department of Frailty Research, Research Institute, National Center for Geriatrics and Gerontology, Obu, Japan.
  • Imagama S; Nagoya City University, Graduate School of Medicine, Nagoya, Japan.
Int J Rheum Dis ; 27(1): e15034, 2024 Jan.
Article en En | MEDLINE | ID: mdl-38287545
ABSTRACT

OBJECTIVE:

This study aimed to determine whether there are associations between laughter, disease activity, frailty, and depression in rheumatoid arthritis (RA) patients.

METHODS:

A total of 240 patients were included in this prospective cohort study on frailty in RA patients between March 2021 and June 2022. Patients were divided into the following four groups according to the frequency of laughter "almost every day," "1-5 days per week," "1-3 days per month," and "never or almost never." Patient characteristics were compared among the four groups by analysis of variance. Factors associated with laughter were identified by multivariable logistic analysis.

RESULTS:

The mean 28-joint Disease Activity Score using CRP was 1.91, with 70.7% of patients in remission and 12.6% in low disease activity. For the "almost every day" (42.5% of patients), "1-5 days per week" (40.0%), "1-3 days per month" (11.3%), and "never or almost never" (6.3%) groups, scores of the Kihon Checklist (KCL) for assessing frailty status were 3.5, 4.6, 7.3, and 8.1 (p < .001), respectively, and scores of the Beck Depression Inventory (BDI-II) were 8.4, 10.7, 15.1, and 16.5 (p < .001), respectively. Multivariable analysis revealed that KCL (OR 0.81, 95% CI 0.73-0.90) and BDI-II (OR 0.91, 95% CI 0.86-0.95) scores were independently associated with the frequency of laughter.

CONCLUSION:

Frailty and depression were associated with laughter in RA patients with controlled disease activity. Interventions aimed at not only disease activity control but also frailty prevention may lead to a life filled with laughter.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Artritis Reumatoide / Fragilidad / Risa Tipo de estudio: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference Límite: Humans Idioma: En Revista: Int J Rheum Dis Asunto de la revista: REUMATOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Artritis Reumatoide / Fragilidad / Risa Tipo de estudio: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference Límite: Humans Idioma: En Revista: Int J Rheum Dis Asunto de la revista: REUMATOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido