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Age-related changes in anti-elastin antibodies in serum from normal and atherosclerotic subjects.
Atherosclerosis ; 63(2-3): 267-71, 1987 Feb.
Article en En | MEDLINE | ID: mdl-3827988
A modified version of the enzyme-linked immunosorbent assay (ELISA), utilising human insoluble aortic elastin, was used for determination of anti-elastin antibodies in serum from normal and atherosclerotic subjects. The age-related changes in their level among healthy persons were investigated. Anti-elastin antibodies were found in all the tested human sera, showing the highest level at the age of 18-20 and the lowest at the age over 60 and especially among atherosclerotic patients. The possible role of the immune system in the turnover of elastin is discussed.
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Arteriosclerosis / Autoanticuerpos / Elastina Límite: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Male / Middle aged Idioma: En Revista: Atherosclerosis Año: 1987 Tipo del documento: Article Pais de publicación: Irlanda
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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Arteriosclerosis / Autoanticuerpos / Elastina Límite: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Male / Middle aged Idioma: En Revista: Atherosclerosis Año: 1987 Tipo del documento: Article Pais de publicación: Irlanda