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Association between ischemic heart disease and dietary intake of lycopene: a case-control study.
Amjadi, Arezoo; Alami, Farkhondeh; Mohammadian, Mohammad Keshavarz; Mirshafaei, Seyed Reza; Azaryan, Fatemeh; Houshiar-Rad, Anahita; Esmaeili, Mina; Shekari, Soheila; Abdollahi, Morteza; Khoshdooz, Sara; Ajami, Marjan; Doaei, Saeid; Gholamalizadeh, Maryam.
Afiliación
  • Amjadi A; Department of Nutrition, School of Nutritional Sciences and Food Technology, Kermanshah University of Medical Sciences, Kermanshah, Iran.
  • Alami F; Student Research Committee, Department of Nutrition, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
  • Mohammadian MK; Department of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran.
  • Mirshafaei SR; Department of Applied Mathematics, Faculty of Mathematical Sciences, Roudsar and Amlash Branch, Islamic Azad University, Roudsar, Iran.
  • Azaryan F; Department of Physiology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
  • Houshiar-Rad A; Department of Nutrition Research, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Esmaeili M; Department of Nutrition Research, National Nutrition and Food Technology Research Institute, School of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Shekari S; Department of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran.
  • Abdollahi M; Department of Nutrition Research, National Nutrition and Food Technology Research Institute; and Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Khoshdooz S; Faculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
  • Ajami M; Department of Food and Nutrition Policy and Planning, National Nutrition and Food Technology Research Institute, School of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Doaei S; Department of Community Nutrition, School of Nutrition and Food Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Gholamalizadeh M; Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Front Nutr ; 10: 1281539, 2023.
Article en En | MEDLINE | ID: mdl-38264195
ABSTRACT

Aim:

The effect of dietary lycopene on ischemic heart disease (IHD) is not clear. Hence, this study aimed to determine the association between dietary lycopene and IHD.

Methods:

This case-control study was conducted on 443 patients with physician confirmed diagnosis of IHD as the case group and 443 healthy individuals as the control group. Data on demographic, medical history, anthropometric, and physical activity of the participants were collected. Food intake was evaluated using a 237-item semi-quantitative food frequency questionnaire (FFQ). The dietary intake of lycopene was assessed using Nutritionist IV software.

Results:

A negative association was found between IHD and lycopene (OR 0.98, CI 95% 0.963-0.996, p = 0.02). The results remained significant after adjustment for age and sex, additional adjustment for dietary intake of calorie and fat, further adjustments for BMI, and additional adjustment for smoking, drinking alcohol, and physical activity. The risk of IHD in people with the highest quartile of dietary intake of lycopene was significantly lower than those with the lowest quartile (OR = 0.67, CI 95% 0.46-0.97, p = 0.036).

Conclusion:

There was a significant inverse relationship between intake of lycopene and IHD. Further prospective studies in different populations are required to elucidate the roles of lycopene against IHD.
Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Observational_studies / Risk_factors_studies Idioma: En Revista: Front Nutr Año: 2023 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Observational_studies / Risk_factors_studies Idioma: En Revista: Front Nutr Año: 2023 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Suiza