Your browser doesn't support javascript.
loading
Berries vs. Disease: Revenge of the Phytochemicals.
Lamenza, Felipe F; Upadhaya, Puja; Roth, Peyton; Shrestha, Suvekshya; Jagadeesha, Sushmitha; Horn, Natalie; Pracha, Hasan; Oghumu, Steve.
Afiliación
  • Lamenza FF; Department of Pathology, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
  • Upadhaya P; Department of Microbiology, The Ohio State University, Columbus, OH 43210, USA.
  • Roth P; Department of Pathology, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
  • Shrestha S; Department of Pathology, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
  • Jagadeesha S; Department of Pathology, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
  • Horn N; Department of Microbiology, The Ohio State University, Columbus, OH 43210, USA.
  • Pracha H; Department of Pathology, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
  • Oghumu S; Department of Pathology, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.
Pharmaceuticals (Basel) ; 17(1)2024 Jan 09.
Article en En | MEDLINE | ID: mdl-38256917
ABSTRACT
Secondary metabolites and phytochemicals in plant-based diets are known to possess properties that inhibit the development of several diseases including a variety of cancers of the aerodigestive tract. Berries are currently of high interest to researchers due to their high dietary source of phytochemicals. Black raspberries (BRB), Rubus occidentalis, are of special interest due to their rich and diverse composition of phytochemicals. In this review, we present the most up-to-date preclinical and clinical data involving berries and their phytochemicals in the chemoprevention of a variety of cancers and diseases. BRBs possess a variety of health benefits including anti-proliferative properties, anti-inflammatory activity, activation of pro-cell-death pathways, modulation of the immune response, microbiome modulation, reduction in oxidative stress, and many more. However, little has been done in both preclinical and clinical settings on the effects of BRB administration in combination with other cancer therapies currently available for patients. With the high potential for BRBs as chemopreventive agents, there is a need to investigate their potential in combination with other treatments to improve therapeutic efficacy.
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Pharmaceuticals (Basel) Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Pharmaceuticals (Basel) Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza