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The prevalence of prescription opioid use and misuse among emergency department patients in The Netherlands.
Holkenborg, Joris; Frenken, Bernice A; Bon, Brigitte van de Kerkhof-Van; Vroegop, Maurice P; Van Meggelen, Mariska G M; Kramers, Cees; Schellekens, Arnt F A; Kraaijvanger, Nicole.
Afiliación
  • Holkenborg J; Emergency Department, Rijnstate Hospital, Arnhem, The Netherlands.
  • Frenken BA; Emergency Department, Rijnstate Hospital, Arnhem, The Netherlands.
  • Bon BVK; Emergency Department, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.
  • Vroegop MP; Emergency Department, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Van Meggelen MGM; Emergency Department, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands.
  • Kramers C; Department of Pharmacology-Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Schellekens AFA; Nijmegen Institute for Science Practitioners in Addiction (NISPA), Nijmegen, The Netherlands.
  • Kraaijvanger N; Department of Psychiatry, Radboud University Medical Center, Nijmegen, The Netherlands.
J Eval Clin Pract ; 30(3): 473-480, 2024 Apr.
Article en En | MEDLINE | ID: mdl-38251860
ABSTRACT
RATIONALE Prescription opioid use and misuse have increased rapidly in many Western countries in the past decade. Patients (mis)using opioids are at risk of presenting to the emergency department (ED) with opioid-related problems. European data concerning prescription opioid (mis)use among the ED population is lacking. AIMS AND

OBJECTIVES:

This study aims to determine prevalence of prescription opioid use, misuse, and opioid use disorder (OUD) among Dutch ED patients. Secondary objectives were to explore factors associated with prescription opioid misuse and the number of patients discharged with a new opioid prescription.

METHODS:

In a cross-sectional multicenter study at three hospitals in the Netherlands, adult ED patients were screened for current prescription opioid use. Opioid users filled out questionnaires regarding opioid (mis)use, and underwent a structured interview to assess OUD criteria. The primary outcomes were prevalence rates of (1) current prescription opioid use, (2) prescription opioid misuse (based on a Current Opioid Misuse Measure [COMM] score > 8), (3) OUD, based on DSM-5 criteria. Independent T-tests, Pearson χ2 and Fisher's Exact tests were used to analyse differences in characteristics between groups.

RESULTS:

A total of 997 patients were screened, of which 15% (n = 150) used prescription opioids. Out of 93 patients assessed, 22.6% (n = 21) showed signs of prescription opioid misuse, and 9.8% (n = 9, 95% CI 4.5-17.8) fulfilled criteria for OUD. A medical history of psychiatric disorder was significantly more common in patients with prescription opioid misuse and OUD.

CONCLUSION:

This study shows that prescription opioid use is relatively common in ED patients in the Netherlands, compared to the overall population. Over one fifth of these patients shows signs of opioid misuse or OUD. Awareness among ED personnel about the high prevalence of prescription opioid (mis)use in their population is critical for signalling opioid-related problems.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Mal Uso de Medicamentos de Venta con Receta / Trastornos Relacionados con Opioides Tipo de estudio: Clinical_trials / Prevalence_studies / Qualitative_research / Risk_factors_studies Límite: Adult / Humans País/Región como asunto: Europa Idioma: En Revista: J Eval Clin Pract Asunto de la revista: PESQUISA EM SERVICOS DE SAUDE Año: 2024 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Mal Uso de Medicamentos de Venta con Receta / Trastornos Relacionados con Opioides Tipo de estudio: Clinical_trials / Prevalence_studies / Qualitative_research / Risk_factors_studies Límite: Adult / Humans País/Región como asunto: Europa Idioma: En Revista: J Eval Clin Pract Asunto de la revista: PESQUISA EM SERVICOS DE SAUDE Año: 2024 Tipo del documento: Article País de afiliación: Países Bajos Pais de publicación: Reino Unido