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Extra-Axial Cavernous Angioma: A Case Report and Review of the Literature.
Hassanzadeh, Shakiba; Gao, Linlin; Alvarado, Anthony M; Camarata, Paul J; Lakis, Nelli S; Haeri, Mohammad.
Afiliación
  • Hassanzadeh S; Department of Pathology and Laboratory Medicine, East Carolina University, Greenville, NC 27834, USA.
  • Gao L; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS 66160, USA.
  • Alvarado AM; Department of Neurosurgery, University of Kansas Medical Center, Kansas City, KS 66160, USA.
  • Camarata PJ; Department of Neurosurgery, University of Kansas Medical Center, Kansas City, KS 66160, USA.
  • Lakis NS; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS 66160, USA.
  • Haeri M; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS 66160, USA.
Neurol Int ; 16(1): 162-185, 2024 Jan 12.
Article en En | MEDLINE | ID: mdl-38251058
ABSTRACT
Cavernous angiomas (CAs) are benign vascular malformations predominantly seen in the brain parenchyma and therefore referred to as intra-axial. Extra-axial dural-based cavernous angiomas, on the other hand, are rare vascular lesions found outside of the brain parenchyma. They occur in the middle fossa and may be easily misdiagnosed as meningiomas due to their extra-axial location. In addition, CAs that are located outside the middle fossa, such as in the convexity, have a better prognosis since they are more surgically accessible. Surgical resection is the main treatment of choice in CAs. However, other options, such as embolization and radiotherapy, may also be considered therapeutic choices or additive treatment options. The pathogenesis of CA and the involvement of other factors (genetics or environmental factors) are still unknown and require further investigation. We are presenting a young man who presented for evaluation of seizure-like events without any family history of neurologic conditions. The physical examination was unremarkable except for a slightly antalgic gait. Imaging studies showed an extra-axial left tentorial mass suggestive of a meningioma, hemangiopericytoma, or other extra-axial lesions. The lesion was resected where its vascular nature was mentioned initially, and the histology proved the diagnosis of cavernous angioma. Here we give an overview of the known pathogenesis, causes, clinical features, and diagnostic and therapeutic options in CA. Better knowledge about CA, its causes, clinical features, and treatment options would help clinicians in early diagnosis and patient management.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies / Screening_studies Idioma: En Revista: Neurol Int Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies / Screening_studies Idioma: En Revista: Neurol Int Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza