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Severe traumatic brain injury and acute kidney injury patients: factors associated with in-hospital mortality and unfavorable outcomes.
de Cássia Almeida Vieira, Rita; de Barros, Gabriela Lima; Paiva, Wellingson Silva; de Oliveira, Daniel Vieira; de Souza, Camila Pedroso Estevam; Santana-Santos, Eduesley; de Sousa, Regina Marcia Cardoso.
Afiliación
  • de Cássia Almeida Vieira R; CAPES Foundation, Ministry of Brazil, Brasilia, Brazil.
  • de Barros GL; School of Nursing, University of Sao Paulo, Sao Paulo, Brazil.
  • Paiva WS; School of Nursing, University of Sao Paulo, Sao Paulo, Brazil.
  • de Oliveira DV; Faculty of Medicine, University of Sao Paulo, Sao Paulo, Brazil.
  • de Souza CPE; Faculty of Medicine, University of Sao Paulo, Sao Paulo, Brazil.
  • Santana-Santos E; Department of Statistical and Actuarial Sciences, University of Western Ontario, London, Canada.
  • de Sousa RMC; Department of Nursing, University of Sergipe, Aracaju, Sergipe, Brazil.
Brain Inj ; 38(2): 108-118, 2024 01 28.
Article en En | MEDLINE | ID: mdl-38247393
ABSTRACT

OBJECTIVE:

The purpose of this study was to identify the occurrence of AKI, and factors associated with in-hospital mortality and unfavorable outcomes in patients with severe traumatic brain injury (TBI) and acute kidney injury (AKI) severity.

METHOD:

A retrospective cohort study which analyzed data with severe TBI between 2013 and 2017. We examined demographic and clinical information, and outcome by in-hospital mortality, and the Glasgow Outcome Scale six months after TBI. We associated factors to in-hospital mortality and unfavorable outcome in severe TBI and AKI with an association test.

RESULTS:

A total of 219 patients were selected, 39.3% had an AKI, and several factors associated with AKI occurrence after severe TBI. Stage 2 or 3 of AKI (OR 12.489; 95% CI = 4.45-37.94) were independent risk for both outcomes in multivariable models, severity injury by the New Trauma Injury Severity Score (OR 0.97; 95% CI = 0.96-0.99) for mortality, and the New Injury Severity Score (OR1.07; 95% CI = 1.04-1.10) and Trauma and Injury Severity Score (OR = 0.98; 95% CI = 0.965-0.997) for unfavorable outcome.

CONCLUSION:

The findings of our study confirmed that AKI severity and severity of injury was also related to increased mortality and unfavorable outcome after severe TBI.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Lesión Renal Aguda / Lesiones Traumáticas del Encéfalo Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Brain Inj Asunto de la revista: CEREBRO Año: 2024 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Lesión Renal Aguda / Lesiones Traumáticas del Encéfalo Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Brain Inj Asunto de la revista: CEREBRO Año: 2024 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Reino Unido