Your browser doesn't support javascript.
loading
Pubertal Status at the Time of Fertility Preservation in Transgender Girls.
Yau, Mabel; Malhotra, Neha R; Steever, John; Baldisserotto, Eva; Lin, Cathy; Fader, Ralph; Oransky, Matthew; Safer, Joshua D.
Afiliación
  • Yau M; Mount Sinai Center for Transgender Medicine and Surgery, New York, New York; Division of Pediatric Endocrinology, Mount Sinai Kravis Children's Hospital, New York, New York. Electronic address: mabel.yau@mssm.edu.
  • Malhotra NR; Division of Pediatric Urology, Mount Sinai Kravis Children's Hospital, New York, New York.
  • Steever J; Division of Adolescent Medicine, Mount Sinai Kravis Children's Hospital, New York, New York.
  • Baldisserotto E; Division of Pediatric Urology, Mount Sinai Kravis Children's Hospital, New York, New York.
  • Lin C; Division of Pediatric Endocrinology, Mount Sinai Kravis Children's Hospital, New York, New York.
  • Fader R; Mount Sinai Center for Transgender Medicine and Surgery, New York, New York; Department of Psychiatry, Mount Sinai Hospital, New York, New York.
  • Oransky M; Mount Sinai Center for Transgender Medicine and Surgery, New York, New York.
  • Safer JD; Mount Sinai Center for Transgender Medicine and Surgery, New York, New York; Division of Endocrinology, Mount Sinai Health System and Icahn School of Medicine at Mount Sinai, New York, New York.
Endocr Pract ; 30(4): 356-359, 2024 Apr.
Article en En | MEDLINE | ID: mdl-38242354
ABSTRACT

BACKGROUND:

Puberty blockade and gender-affirming hormone therapy can impair fertility. Counseling on fertility preservation is important before initiation of therapy. Our study aimed to assess Tanner staging and the presence of virilizing secondary sex characteristics at the time of sperm collection and correlate the viability of sperm with the Tanner staging and degree of virilization.

METHODS:

A retrospective chart review of 23 transgender girls referred to pediatric urology at our academic pediatric transgender clinic for fertility preservation counseling was performed. At the initial visit before treatment, pubertal staging along with the assessment of virilizing secondary characteristics was performed. The semen analyses were evaluated for volume, sperm concentration, total sperm count, motility, and total motile count.

RESULTS:

Of the first 23 transgender girls evaluated and counseled, 8 transgender females successfully produced a sperm sample for cryopreservation. The average testicular volume was 18.5 ml and ranged from 12 ml to 20 ml. The median semen parameters were at or above the 2021 World Health Organization threshold. The 8 transgender females who successfully underwent fertility preservation presented with at least 1 secondary sex characteristic. In 1 subject with Tanner stage 3 pubic hair development and a testicular volume of 12 ml, only voice change was reported. Facial hair and laryngeal prominence were not present on examination.

CONCLUSION:

More than a third of our patients who accepted a referral to pediatric urology agreed to produce a sperm sample for cryopreservation. All of these patients successfully preserved sperm. With counseling and early referral to pediatric urology, a high percentage of fertility preservation in transgender girls was achieved.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Preservación de la Fertilidad / Personas Transgénero Límite: Child / Female / Humans / Male Idioma: En Revista: Endocr Pract Asunto de la revista: ENDOCRINOLOGIA Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Preservación de la Fertilidad / Personas Transgénero Límite: Child / Female / Humans / Male Idioma: En Revista: Endocr Pract Asunto de la revista: ENDOCRINOLOGIA Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos