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Discharge Information About Adverse Drug Reactions Indicates Lower Self-Reported Adverse Drug Reactions and Fewer Concerns in Patients After Percutaneous Coronary Intervention.
Pettersen, Trond Røed; Schjøtt, Jan; Allore, Heather; Bendz, Bjørn; Borregaard, Britt; Fridlund, Bengt; Hadjistavropoulos, Heather D; Larsen, Alf Inge; Nordrehaug, Jan Erik; Rasmussen, Trine Bernholdt; Rotevatn, Svein; Valaker, Irene; Wentzel-Larsen, Tore; Norekvål, Tone M.
Afiliación
  • Pettersen TR; Department of Heart Disease, Haukeland University Hospital, Bergen, Norway. Electronic address: trond.roed.pettersen@helse-bergen.no.
  • Schjøtt J; Department of Medical Biochemistry and Pharmacology, Haukeland University Hospital, Bergen, Norway.
  • Allore H; Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
  • Bendz B; Department of Cardiology, Oslo University Hospital, Oslo, Norway.
  • Borregaard B; Department of Cardiology, Odense University Hospital, Odense, Denmark.
  • Fridlund B; Centre of Interprofessional Collaboration within Emergency Care (CICE), Linnaeus University, Växjö, Sweden.
  • Hadjistavropoulos HD; Department of Psychology, University of Regina, Regina, Canada.
  • Larsen AI; Department of Cardiology, Stavanger University Hospital, Stavanger, Norway.
  • Nordrehaug JE; Department of Clinical Science, University of Bergen, Bergen, Norway.
  • Rasmussen TB; Department of Cardiology, Herlev and Gentofte University Hospital, Hellerup, Denmark.
  • Rotevatn S; Department of Heart Disease, Haukeland University Hospital, Bergen, Norway.
  • Valaker I; Faculty of Health and Social Sciences, Western Norway University of Applied Sciences, Campus Førde, Norway.
  • Wentzel-Larsen T; Centre for Clinical Research, Haukeland University Hospital, Bergen, Norway.
  • Norekvål TM; Department of Heart Disease, Haukeland University Hospital, Bergen, Norway.
Heart Lung Circ ; 33(3): 350-361, 2024 Mar.
Article en En | MEDLINE | ID: mdl-38238118
ABSTRACT

AIM:

There are discrepancies between the information patients desire about adverse drug reactions (ADRs) and the information they receive from healthcare providers; this is an impediment to shared decision-making. This study aimed to establish whether patients received information about ADRs resulting from prescribed pharmacotherapy, before hospital discharge, after percutaneous coronary intervention (PCI) and to determine whether receiving information about ADRs was associated with incidence of self-reported ADRs or concerns related to prescribed pharmacotherapy.

METHODS:

CONCARDPCI, a prospective multicentre cohort study including 3,417 consecutive patients after PCI, was conducted at seven high-volume referral PCI centres in two Nordic countries. Clinical data were collected from patients' medical records and national quality registries. Patient-reported outcome measures were registered 2 months (T1), 6 months (T2), and 12 months (T3) after discharge. Covariate-adjusted logistic regression yielded adjusted odds ratios (aORs) with 95% confidence intervals (CIs).

RESULTS:

At discharge, 38% of participants had been informed about potential ADRs. For these patients, the incidence of self-reported ADRs was significantly lower at T1 (aOR 0.61, 95% CI 0.50-0.74; p<0.001), T2 (aOR 0.60, 95% CI 0.49-0.74; p<0.001), and T3 (aOR 0.57, 95% CI 0.46-0.71; p<0.001). Those who were not informed reported higher levels of concern about prescribed pharmacotherapy at all measuring points (p<0.001 for all comparisons). Those living alone (aOR 0.73, 95% CI 0.57-0.92; p=0.008), who were female (aOR 0.57, 95% CI 0.44-0.72; p<0.001), and with three or more versus no comorbidities (aOR 0.61, 95% CI 0.44-0.84; p=0.002) were less likely to receive information.

CONCLUSION:

A substantial proportion of patients were not informed about potential ADRs from prescribed pharmacotherapy after PCI. Patients informed about ADRs had lower incidences of self-reported ADRs and fewer concerns about prescribed pharmacotherapy.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos / Intervención Coronaria Percutánea Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference Límite: Female / Humans / Male Idioma: En Revista: Heart Lung Circ Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 2024 Tipo del documento: Article Pais de publicación: Australia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos / Intervención Coronaria Percutánea Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference Límite: Female / Humans / Male Idioma: En Revista: Heart Lung Circ Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA Año: 2024 Tipo del documento: Article Pais de publicación: Australia