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Trend in antibiotic prescription at pediatric primary emergency medical centers in Japan: A multi-center, cross-sectional study.
Otake, Shogo; Shoji, Takayo; Yamada, Kenta; Kimura, Makoto; Myojin, Shota; Kamiyoshi, Naohiro; Ochi, Fumihiro; Nezu, Mari; Ishida, Akihito; Miyairi, Isao; Kasai, Masashi.
Afiliación
  • Otake S; Department of Pediatrics, Kobe University Graduate School of Medicine, Hyogo, Japan; Division of Infectious Disease, Department of Pediatrics, Kobe Children's Hospital, Hyogo, Japan. Electronic address: shogo.ohtake@gmail.com.
  • Shoji T; Department of Infectious Diseases, Shizuoka Children's Hospital, Shizuoka, Japan.
  • Yamada K; Department of Pediatrics, University of Fukui Hospital, Fukui, Japan.
  • Kimura M; Kobe Children's Primary Emergency Medical Center, Hyogo, Japan.
  • Myojin S; Division of Infectious Diseases, National Center for Child Health and Development, Tokyo, Japan.
  • Kamiyoshi N; Department of Pediatrics, Japanese Red Cross Society Himeji Hospital, Hyogo, Japan.
  • Ochi F; Department of Pediatrics, Ehime Prefectural Niihama Hospital, Ehime, Japan.
  • Nezu M; Department of Clinical Epidemiology, Hyogo Medical University, Hyogo, Japan.
  • Ishida A; Kobe Children's Primary Emergency Medical Center, Hyogo, Japan.
  • Miyairi I; Department of Pediatrics, Hamamatsu University School of Medicine, Shizuoka, Japan; Department of Microbiology, Immunology, and Biochemistry, University of Tennessee Health Science Center, TN, USA.
  • Kasai M; Division of Infectious Disease, Department of Pediatrics, Kobe Children's Hospital, Hyogo, Japan.
J Infect Chemother ; 30(7): 616-620, 2024 Jul.
Article en En | MEDLINE | ID: mdl-38237860
ABSTRACT

INTRODUCTION:

Antimicrobial resistance is a global issue, and implementation of antimicrobial stewardship programs in outpatient settings is crucial. Japan has also focused on outpatient oral antimicrobial stewardship programs and difficulties in standardizing prescriptions have led to overprescription in primary emergency medical centers. There is a lack of research investigating the antibiotic prescription status of pediatric primary emergency medical centers and the benchmark prescription rates in pediatric outpatient settings.

METHODS:

We conducted a multi-center, cross-sectional study of seven pediatric primary emergency medical centers located in five prefectures of Japan. We retrospectively extracted data from health claims or directly obtained them from charts at each institution and evaluated trends in the antibiotic prescription rate based on the AWaRe classification between April 2016 and December 2019.

RESULTS:

Our study included 383,525 encounters, with the most common infectious disease diagnosis being acute upper respiratory tract infection in 93,449 cases (24.4 %). The antibiotic prescription rate during the study period was 7.4 %, representing a decrease of 46 %, from 10.2 % in 2016 to 5.5 % in 2019. The percentage of prescriptions in the Access group increased at all institutions; however, it exceeded 60 % in only three facilities in 2019. The percentage of third-generation cephalosporins varied among facilities, ranging from 1.7 % to 59.4 %, as of 2019.

CONCLUSIONS:

For pediatric primary emergency medical centers where antimicrobial stewardship programs are implemented, we suggest 5 % as a reasonable benchmark level for the antibiotic prescription rate. Prescribing the antibiotics in the Access groups less frequently remains a domestic challenge in Japan.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Programas de Optimización del Uso de los Antimicrobianos / Antibacterianos Tipo de estudio: Clinical_trials / Observational_studies / Prevalence_studies Límite: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male / Newborn País/Región como asunto: Asia Idioma: En Revista: J Infect Chemother Asunto de la revista: MICROBIOLOGIA / TERAPIA POR MEDICAMENTOS Año: 2024 Tipo del documento: Article Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Programas de Optimización del Uso de los Antimicrobianos / Antibacterianos Tipo de estudio: Clinical_trials / Observational_studies / Prevalence_studies Límite: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male / Newborn País/Región como asunto: Asia Idioma: En Revista: J Infect Chemother Asunto de la revista: MICROBIOLOGIA / TERAPIA POR MEDICAMENTOS Año: 2024 Tipo del documento: Article Pais de publicación: Países Bajos