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Camellia annamensis (Theaceae): phytochemical analysis, cytotoxic, antioxidative, and antimicrobial activities.
Linh, Nguyen Ngoc; Huong, Nguyen Thi Mai; Dai, Do Ngoc; Giang, Nguyen Thi An; Huong, Le Thi; Thuy, Ta Thi Thu; Son, Ninh The.
Afiliación
  • Linh NN; Faculty of Pharmacy, Thanh Do University, Hoai Duc, Hanoi, Vietnam.
  • Huong NTM; Faculty of Food Technology, University of Economics-Technology for Industry, Hai Ba Trung, Hanoi, Vietnam.
  • Dai DN; Faculty of Agriculture, Forestry and Fishery, Nghean University of Economics, Vinh, Nghean, Vietnam.
  • Giang NTA; Faculty of Biology, College of Education, Vinh University, Vinh, Nghean, Vietnam.
  • Huong LT; Faculty of Biology, College of Education, Vinh University, Vinh, Nghean, Vietnam.
  • Thuy TTT; Institute of Biotechnology and Food Technology, Ha Noi Open University, Hai Ba Trung, Hanoi, Vietnam.
  • Son NT; Institute of Chemistry, Vietnam Academy Science and Technology (VAST), Cau Giay, Hanoi, Vietnam.
Nat Prod Res ; : 1-7, 2024 Jan 15.
Article en En | MEDLINE | ID: mdl-38225908
ABSTRACT
Cytotoxic, antioxidative, and antimicrobial activities of Camellia annamensis, and its chemical compositions were first provided in the current study. Phenolic contents in the methanol extracts of its leaves and flowers were 222.73 ± 0.09 and 64.44 ± 0.08 mg GAE/g extract, whereas flavonoid contents in these parts were 108.80 ± 0.28 and 131.26 ± 0.39 mg rutin/g extract, respectively. By using HPLC-DAD analysis, gallic acid (43.72 ± 0.09 - 81.89 ± 1.83 mg/g) and (-)-epigallocatechin gallate (67.31 ± 1.26 - 70.68 ± 7.82 mg/g) were identified as the major compounds. C. annamensis leaf and flower extracts were moderately cytotoxic against A549, HT-29, SK-Mel-2, MCF-7, HepG2, HeLa, and MKN-7. Particularly, they are better than the standards trolox (IC50 7.57 ± 0.23 µg/mL) in lipid peroxidation inhibitory evaluation, and streptomycin (IC50/MIC = 45.34-50.34/128-256 µg/mL) in antimicrobial assay against the Gram-positive bacteria Enterococcus faecalis ATCC299212, Staphylococcus aureus ATCC25923, and the Gram-negative bacterium Salmonella enterica ATCC13076.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Nat Prod Res Año: 2024 Tipo del documento: Article País de afiliación: Vietnam Pais de publicación: Reino Unido
Texto completo
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Imprimir
XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Nat Prod Res Año: 2024 Tipo del documento: Article País de afiliación: Vietnam Pais de publicación: Reino Unido