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Regional disparities, age-related changes and sex-related differences in knee osteoarthritis.
Di, Jingkai; Bai, Jiang; Zhang, Junrui; Chen, Jiaoyang; Hao, Yuxuan; Bai, Jiaqi; Xiang, Chuan.
Afiliación
  • Di J; Department of Orthopedics, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
  • Bai J; The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
  • Zhang J; The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
  • Chen J; The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
  • Hao Y; The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
  • Bai J; The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
  • Xiang C; Department of Orthopedics, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China. chuanxiang@sxmu.edu.cn.
BMC Musculoskelet Disord ; 25(1): 66, 2024 Jan 15.
Article en En | MEDLINE | ID: mdl-38225636
ABSTRACT

BACKGROUND:

The objective of the study is to analyse the regions, age and sex differences in the incidence of knee osteoarthritis (KOA).

METHODS:

Data were extracted from the global burden of diseases (GBD) 2019 study, including incidence, years lived with disability (YLD), disability-adjusted life-years (DALYs) and risk factors. Estimated annual percentage changes (EAPCs) were calculated to quantify the temporal trends in age standardized rate (ASR) of KOA. Paired t-test, paired Wilcoxon signed-rank test and spearman correlation were performed to analyze the association of sex disparity in KOA and socio-demographic index (SDI).

RESULTS:

There were significant regional differences in the incidence of knee osteoarthritis. In 2019, South Korea had the highest incidence of knee osteoarthritis (474.85,95%UI413.34-539.64) and Thailand had the highest increase in incidence of knee osteoarthritis (EAPC = 0.56, 95%CI = 0.54-0.58). Notably, higher incidence, YLD and DALYs of knee osteoarthritis were associated with areas with a high socio-demographic index (r = 0.336, p < 0.001; r = 0.324, p < 0.001; r = 0.324, p < 0.001). In terms of age differences, the greatest increase in the incidence of knee osteoarthritis was between the 35-39 and 40-44 age groups. (EAPC = 0.52, 95%CI = 0.40-0.63; 0.47, 95%CI = 0.36-0.58). In addition, there were significant sex differences in the disease burden of knee osteoarthritis (P < 0.001).

CONCLUSIONS:

The incidence of knee osteoarthritis is significantly different with regions, age and sex.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Osteoartritis de la Rodilla Tipo de estudio: Diagnostic_studies / Incidence_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference Límite: Female / Humans / Male País/Región como asunto: Asia Idioma: En Revista: BMC Musculoskelet Disord Asunto de la revista: FISIOLOGIA / ORTOPEDIA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Osteoartritis de la Rodilla Tipo de estudio: Diagnostic_studies / Incidence_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference Límite: Female / Humans / Male País/Región como asunto: Asia Idioma: En Revista: BMC Musculoskelet Disord Asunto de la revista: FISIOLOGIA / ORTOPEDIA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido