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Giant cell myocarditis with prolonged cardiac standstill after drug-induced hypersensitivity syndrome: a case report.
Ono, Ryohei; Kohno, Hiroki; Kaminota, Sae; Aoki, Kaoruko; Kato, Hirotoshi; Iwahana, Togo; Aihara, Takanori; Ota, Masayuki; Matsumiya, Goro; Kobayashi, Yoshio.
Afiliación
  • Ono R; Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba, Japan.
  • Kohno H; Department of Cardiovascular Surgery, Chiba University Graduate School of Medicine, Chiba, Japan.
  • Kaminota S; Chiba University School of Medicine, Chiba, Japan.
  • Aoki K; Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba, Japan.
  • Kato H; Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba, Japan.
  • Iwahana T; Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba, Japan.
  • Aihara T; Department of Pathology, Chiba University Hospital, Chiba, Japan.
  • Ota M; Department of Diagnostic Pathology, Graduate School of Medicine, Chiba University, Chiba, Japan.
  • Matsumiya G; Department of Cardiovascular Surgery, Chiba University Graduate School of Medicine, Chiba, Japan.
  • Kobayashi Y; Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba, Japan.
ESC Heart Fail ; 11(2): 805-810, 2024 Apr.
Article en En | MEDLINE | ID: mdl-38221824
ABSTRACT
Giant cell myocarditis (GCM) is a rare but fatal disease that can lead to cardiac failure. Survival with a cardiac standstill requires mechanical circulatory support or a biventricular assist device (BiVAD) and prolonged survival is extremely rare. Drug-induced hypersensitivity syndrome (DIHS) is a severe cutaneous adverse reaction. Some cases of DIHS are reportedly associated with the onset of GCM. We present a case of a 28-year-old woman who developed GCM during steroid tapering after DIHS. She went into continuous cardiac standstill but survived for 74 days under BiVAD support. Our case is noteworthy because the histopathologic specimens obtained on three occasions contributed to the diagnosis of this particular condition over time. We also reviewed previous literature on concomitant cases of GCM and DIHS. We found that two are potentially associated and most cases of GCM occur within 3 months of DIHS during steroid tapering.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Insuficiencia Cardíaca / Miocarditis Límite: Adult / Female / Humans Idioma: En Revista: ESC Heart Fail Año: 2024 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Insuficiencia Cardíaca / Miocarditis Límite: Adult / Female / Humans Idioma: En Revista: ESC Heart Fail Año: 2024 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido