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Supraglottic jet oxygenation and ventilation improves oxygenation during endoscopic retrograde cholangiopancreatography: a randomized controlled clinical trial.
Su, Dan; Zhang, Wei; Li, Jingze; Tan, Xi; Wei, Huafeng; Wang, Yinglin; Ji, Zhonghua.
Afiliación
  • Su D; Department of Anesthesia, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200120, China.
  • Zhang W; Department of Anesthesia, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200120, China.
  • Li J; Endoscopy Center, Department of Gastroenterology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200120, China.
  • Tan X; Endoscopy Center, Department of Gastroenterology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200120, China.
  • Wei H; Department of Anesthesiology and Critical Care Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
  • Wang Y; Department of Anesthesia, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200120, China. 13907553360@163.com.
  • Ji Z; Department of Anesthesia, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200120, China. 2105800@tongji.edu.cn.
BMC Anesthesiol ; 24(1): 21, 2024 Jan 12.
Article en En | MEDLINE | ID: mdl-38216874
ABSTRACT

PURPOSE:

Hypoxia is one of the most frequent adverse events under deep sedation in the semiprone position. We hypothesized that supraglottic jet oxygenation and ventilation (SJOV) via Wei nasal jet tube (WNJ) can reduce the incidence of hypoxia in patients under deep sedation during endoscopic retrograde cholangiopancreatography (ERCP).

METHODS:

A total of 171 patients were divided into three groups N group, supplementary oxygen via a nasopharyngeal airway (4-6 L/min); W group, supplementary oxygen via WNJ (4-6 L/min); WS group, SJOV via WNJ. The primary outcome was the incidence of adverse events, including sedation-related adverse events [SRAEs, hypoxemia (SpO2 = 75-89% lasted less than 60 s); severe hypoxemia (SpO2 < 75% at any time or SpO2 < 90% lasted more than 60 s] and subclinical respiratory depression (SpO2 = 90-95%). Other intraoperative and post-operative adverse events were also recorded as secondary outcomes.

RESULTS:

Compared with the N group, the incidence of hypoxemia and subclinical respiratory depression in the WS group was significantly lower (21% vs. 4%, P = 0.005; 27% vs. 6%, P = 0.002). Compared with Group W, the incidence of hypoxemia and subclinical respiratory depression in Group WS was also significantly less frequent (20% vs. 4%, P = 0.009; 21% vs. 6%, P = 0.014). No severe hypoxia occurred in the group WS, while four and one instances were observed in the group N and group W respectively. There were no significant differences in other adverse events among the three groups.

CONCLUSION:

SJOV can effectively improve oxygenation during ERCP in deeply sedated semiprone patients.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Insuficiencia Respiratoria / Anestesia Tipo de estudio: Clinical_trials / Etiology_studies Límite: Humans Idioma: En Revista: BMC Anesthesiol Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Insuficiencia Respiratoria / Anestesia Tipo de estudio: Clinical_trials / Etiology_studies Límite: Humans Idioma: En Revista: BMC Anesthesiol Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido