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Pancreatic cysts: can surveillance interval for small low-risk lesions be lengthened?
Chong, Jingli; Wee, Nicole Kessa; Tan, Cher Heng; Low, Hsien Min; Chew, Wei Da; Vu, Charles Kien Fong; Lee, Chau Hung.
Afiliación
  • Chong J; Department of Diagnostic Radiology, Tan Tock Seng Hospital, Singapore, Singapore.
  • Wee NK; Department of Diagnostic Radiology, Tan Tock Seng Hospital, Singapore, Singapore.
  • Tan CH; Department of Diagnostic Radiology, Tan Tock Seng Hospital, Singapore, Singapore.
  • Low HM; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.
  • Chew WD; Department of Diagnostic Radiology, Tan Tock Seng Hospital, Singapore, Singapore.
  • Vu CKF; Department of Gastroenterology and Hepatology, Tan Tock Seng Hospital, Singapore, Singapore.
  • Lee CH; Department of Gastroenterology and Hepatology, Tan Tock Seng Hospital, Singapore, Singapore.
Acta Radiol ; 65(5): 406-413, 2024 May.
Article en En | MEDLINE | ID: mdl-38196245
ABSTRACT

BACKGROUND:

Surveillance of pancreatic cysts are necessary due to risk of malignant transformation. However, reported progression rates to advanced neoplasia are variable and the high frequency of surveillance scans may pose a considerable burden on healthcare resources.

PURPOSE:

To validate the effectiveness of the Fukuoka Guidelines surveillance regime and determine if a longer surveillance interval can be established. MATERIAL AND

METHODS:

All magnetic resonance imaging (MRI) studies of the pancreas performed at our institution between January 2014 and December 2016 with at least one pancreatic cystic lesion and follow-up MRI or computed tomography (CT) over at least two years were reviewed for size, worrisome feature (WF), and high-risk stigmata (HRS) at diagnosis and follow-up imaging (up to year 6). Reference standards for advanced neoplasia were based on endoscopic ultrasound, fine needle aspiration cytology, or the presence of ≥2 WF or ≥1 HRS on imaging. Comparison of MRI features of progression and outcomes of diagnostic endpoints between lesions <20 mm and ≥20 mm was performed.

RESULTS:

A total of 270 patients were included (201 cysts <20 mm, 69 cysts ≥20 mm). Compared with cysts <20 mm, cysts ≥20 mm were more likely to be associated with WF or HRS (40.6% vs. 12.4%; P ≤0.00001), demonstrate increase in size of ≥5 mm in two years (20.3% vs. 10.9%; P = 0.049), and develop advanced neoplasia (24.6% vs. 0.5%; P <0.00001).

CONCLUSION:

Pancreatic cysts <20 mm have a low risk of developing WF and HRS and surveillance interval may be lengthened.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Quiste Pancreático / Imagen por Resonancia Magnética / Tomografía Computarizada por Rayos X Tipo de estudio: Etiology_studies / Guideline / Risk_factors_studies / Screening_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Acta Radiol Año: 2024 Tipo del documento: Article País de afiliación: Singapur Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Quiste Pancreático / Imagen por Resonancia Magnética / Tomografía Computarizada por Rayos X Tipo de estudio: Etiology_studies / Guideline / Risk_factors_studies / Screening_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Acta Radiol Año: 2024 Tipo del documento: Article País de afiliación: Singapur Pais de publicación: Reino Unido