Theoretical hypothesis in a direct electron transfer between non-interacting Fe-S proteins within an artificial fusion.
FEMS Microbiol Lett
; 3712024 01 09.
Article
en En
| MEDLINE
| ID: mdl-38196139
ABSTRACT
Reduction of CO2 to formate utilizing formate dehydrogenases (FDHs) has been attempted biologically and electrochemically. However, the conversion efficiency is very low due to the low energy potential of electron donors and/or electron competition with other electron acceptors. To overcome such a low conversion efficiency, I focused on a direct electron transfer between two unrelated redox enzymes for the efficient reduction of CO2 and utilized the quantum mechanical magnetic properties of the [Fe-S] ([iron-sulfur]) cluster to develop a novel electron path. Using this electron path, we connected non-interacting carbon monoxide dehydrogenase and FDH, constructing a synthetic carbon monoxideformate oxidoreductase as a single functional enzyme complex in the previous study. Here, a theoretical hypothesis that can explain the direct electron transfer phenomenon based on the magnetic properties of the [Fe-S] cluster is proposed.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Dióxido de Carbono
/
Electrones
Idioma:
En
Revista:
FEMS Microbiol Lett
Año:
2024
Tipo del documento:
Article
Pais de publicación:
Reino Unido