Risk factors for severe disease and mortality in children with COVID-19.
Heliyon
; 10(1): e23629, 2024 Jan 15.
Article
en En
| MEDLINE
| ID: mdl-38192840
ABSTRACT
Background:
Pediatric COVID-19 patients have lower rates of hospitalization and fatal outcomes compared to adults with COVID-19; however, children represent a challenge in the detection, diagnosis, and treatment of COVID-19. Our aim was to determine the risk factors for hospital admission, invasive mechanical ventilation, and mortality in pediatric COVID-19 patients in Mexico during the COVID-19 pandemic. Material andmethods:
A retrospective cohort of pediatric patients with COVID-19 from February 2020 to April 2021 was reported on the National Epidemiological Surveillance System for Viral Respiratory Disease (SISVER) platform.Results:
Among the 104,133 patients included in our study, 6214 were hospitalized, and 621 patients underwent invasive mechanical ventilation. A total of 0.65 % died during hospitalization. Children aged <12 months (odds ratio [OR] 17.1; 95 % confidence interval [CI] 15.9-19.4, p < 0.001), 1-4 years (OR 3.69; 95 % CI 3.2-4.1, p < 0.001), 5-9 years (OR 1.86; 95 % CI 1.66-2.08, p < 0.001), and 10-14 years (OR 1.23; 95 % CI 1.11-1.37, p < 0.001), and those diagnosed with diabetes (OR 2.32; 95 % CI 1.68-3.20, p < 0.001) and obesity (OR 1.24; 95 % CI 1.04-1.48, p = 0.015) were associated with hospital admission. Renal disease (OR 3.85; 95 % CI 2.25-6.59, p < 0.001) was associated with invasive mechanical ventilation. Pneumonia (OR 15.9; 95 % CI 12.6-20.1, p < 0.001) and renal disease (OR 3.85; 95 % CI 2.25-6.59, p value < 0.001) were associated with death.Conclusion:
Pneumonia increases the risk of death. The youngest age group has a higher risk of hospital admission. Comorbidities such as renal disease or immunosuppression increase the risk of death in all age groups.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Tipo de estudio:
Etiology_studies
/
Risk_factors_studies
Idioma:
En
Revista:
Heliyon
Año:
2024
Tipo del documento:
Article
País de afiliación:
México
Pais de publicación:
Reino Unido