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Psychological profiles and prescription opioid misuse, craving, and withdrawal in people with chronic pain.
Esteve, R; Barrado-Moreno, V; Ramírez-Maestre, C; Serrano-Ibáñez, E R; de la Vega, R; Ruiz-Párraga, G T; Sainero-Tirado, G; Fernández Baena, M; Jensen, M; López-Martínez, A E.
Afiliación
  • Esteve R; Facultad de Psicología y Logopedia, Universidad de Málaga, Andalucía Tech, Málaga, Spain.
  • Barrado-Moreno V; Instituto de Investigaciones Biomédicas de Málaga (IBIMA), Málaga, Spain.
  • Ramírez-Maestre C; Facultad de Psicología y Logopedia, Universidad de Málaga, Andalucía Tech, Málaga, Spain.
  • Serrano-Ibáñez ER; Instituto de Investigaciones Biomédicas de Málaga (IBIMA), Málaga, Spain.
  • de la Vega R; Facultad de Psicología y Logopedia, Universidad de Málaga, Andalucía Tech, Málaga, Spain.
  • Ruiz-Párraga GT; Instituto de Investigaciones Biomédicas de Málaga (IBIMA), Málaga, Spain.
  • Sainero-Tirado G; Facultad de Psicología y Logopedia, Universidad de Málaga, Andalucía Tech, Málaga, Spain.
  • Fernández Baena M; Instituto de Investigaciones Biomédicas de Málaga (IBIMA), Málaga, Spain.
  • Jensen M; Facultad de Psicología y Logopedia, Universidad de Málaga, Andalucía Tech, Málaga, Spain.
  • López-Martínez AE; Instituto de Investigaciones Biomédicas de Málaga (IBIMA), Málaga, Spain.
Eur J Pain ; 28(6): 943-959, 2024 Jul.
Article en En | MEDLINE | ID: mdl-38189159
ABSTRACT

BACKGROUND:

The negative consequences of prescription opioid misuse and opioid use disorder make it relevant to identify factors associated with this problem in individuals with chronic pain. This cross-sectional study aimed at identifying subgroups of people with chronic pain based on their psychological profiles, prescription opioid misuse, craving, and withdrawal.

METHODS:

The sample comprised 185 individuals with chronic pain. We performed hierarchical cluster analysis on impulsivity, anxiety sensitivity, pain acceptance, pain intensity, opioid misuse, craving, and withdrawal.

RESULTS:

The four-cluster solution was the optimal one. Misuse, craving, and anxiety sensitivity were higher among people in the Severe-problems cluster than among people in the other three clusters. Withdrawal was the highest in the High-withdrawal cluster. Impulsivity was higher among people in the Severe-problems and High-withdrawal clusters than those in the Moderate-problems and Mild-problems clusters. Pain acceptance was higher among people in the Mild-problems cluster than among people in the other three clusters. Anxiety sensitivity and misuse were higher among people in the Moderate-problems cluster than among people in the Mild-problems cluster.

CONCLUSIONS:

These results support that impulsivity, anxiety sensitivity, and pain acceptance are useful constructs to identify subgroups of people with chronic pain according to their level of prescription opioid misuse, craving, and withdrawal. The results of this study may help in selecting the early intervention most suitable for each of the identified profiles.

SIGNIFICANCE:

The psychological profile of individuals with chronic pain, prescription opioid misuse, craving, and withdrawal is characterized by fearing anxiety-related symptoms due to the catastrophic interpretation of such symptoms and reacting impulsively to negative moods. In contrast, participants with high pain acceptance had less prescription opioid misuse, craving, and withdrawal. The profiles identified in this study could help clinicians select targets for intervention among profiles with similar needs and facilitate early interventions to prevent opioid misuse onset or aggravation.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ansiedad / Síndrome de Abstinencia a Sustancias / Dolor Crónico / Mal Uso de Medicamentos de Venta con Receta / Ansia / Analgésicos Opioides / Trastornos Relacionados con Opioides Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Eur J Pain Asunto de la revista: NEUROLOGIA / PSICOFISIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: España Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ansiedad / Síndrome de Abstinencia a Sustancias / Dolor Crónico / Mal Uso de Medicamentos de Venta con Receta / Ansia / Analgésicos Opioides / Trastornos Relacionados con Opioides Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Eur J Pain Asunto de la revista: NEUROLOGIA / PSICOFISIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: España Pais de publicación: Reino Unido