Your browser doesn't support javascript.
loading
Tunable theranostics: innovative strategies in combating oral cancer.
Uthman, Asmaa; Al-Rawi, Noor; Saeed, Musab Hamed; Eid, Bassem; Al-Rawi, Natheer H.
Afiliación
  • Uthman A; Department of Diagnostic and Surgical Dental Sciences, College of Dentistry, Gulf Medical University, Ajman, United Arab Emirates.
  • Al-Rawi N; Department of Pharmaceutics and Pharmaceutical Technology, University of Sharjah, Sharjah, United Arab Emirates.
  • Saeed MH; Department of Clinical Sciences, College of Dentistry, Ajman University, Ajman, United Arab Emirates.
  • Eid B; Ajman University, Centre of Medical and Bio-allied Health Sciences Research,, Ajman, United Arab Emirates.
  • Al-Rawi NH; Department of Restorative Dental Sciences, College of Dentistry, Gulf Medical University, Ajman, Ajman, United Arab Emirates.
PeerJ ; 12: e16732, 2024.
Article en En | MEDLINE | ID: mdl-38188167
ABSTRACT

Objective:

This study aims to assess and compare the potential of advanced nano/micro delivery systems, including quantum dots, carbon nanotubes, magnetic nanoparticles, dendrimers, and microneedles, as theranostic platforms for oral cancer. Furthermore, we seek to evaluate their respective advantages and disadvantages over the past decade. Materials and

Methods:

A comprehensive literature search was performed using Google Scholar and PubMed, with a focus on articles published between 2013 and 2023. Search queries included the specific advanced delivery system as the primary term, followed by oral cancer as the secondary term (e.g., "quantum dots AND oral cancer," etc.).

Results:

The advanced delivery platforms exhibited notable diagnostic and therapeutic advantages when compared to conventional techniques or control groups. These benefits encompassed improved tumor detection and visualization, enhanced precision in targeting tumors with reduced harm to neighboring tissues, and improved drug solubility and distribution, leading to enhanced drug absorption and tumor uptake.

Conclusion:

The findings suggest that advanced nano/micro delivery platforms hold promise for addressing numerous challenges associated with chemotherapy. By enabling precise targeting of cancerous cells, these platforms have the potential to mitigate adverse effects on surrounding healthy tissues, thus encouraging the development of innovative diagnostic and therapeutic strategies for oral cancer.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Boca / Nanotubos de Carbono / Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Revista: PeerJ Año: 2024 Tipo del documento: Article País de afiliación: Emiratos Árabes Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Boca / Nanotubos de Carbono / Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Revista: PeerJ Año: 2024 Tipo del documento: Article País de afiliación: Emiratos Árabes Unidos Pais de publicación: Estados Unidos