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Effectiveness of acupuncture combined with artificial tears in managing dry eye syndrome: A systematic review and meta-analysis.
Wang, Ying; Peng, Jun; Xiao, Li; Deng, Ying; Lu, Jing; Zhou, Ya-Sha; Yang, Yi-Jing; Peng, Qing-Hua.
Afiliación
  • Wang Y; Hunan University of Chinese Medicine, Changsha, China.
  • Peng J; Hunan University of Chinese Medicine, Changsha, China.
  • Xiao L; Institute of Ophthalmology and Otolaryngology of Chinese Medicine, Changsha, China.
  • Deng Y; Hunan University of Chinese Medicine, Changsha, China.
  • Lu J; Hunan University of Chinese Medicine, Changsha, China.
  • Zhou YS; Hunan University of Chinese Medicine, Changsha, China.
  • Yang YJ; Hunan University of Chinese Medicine, Changsha, China.
  • Peng QH; Hunan University of Chinese Medicine, Changsha, China.
Medicine (Baltimore) ; 103(1): e36374, 2024 Jan 05.
Article en En | MEDLINE | ID: mdl-38181299
ABSTRACT

BACKGROUND:

Dry eye syndrome is an ocular surface disease with high incidence. Acupuncture combined with artificial tears is effective for treating dry eye syndrome. This study aimed to evaluate the evidence for the efficacy of acupuncture combined with artificial tears in dry eye syndrome by conducting a systematic review and meta-analysis.

METHODS:

A systematic online search was performed from the date of database establishment to July 1, 2023. The study groups that addressed acupuncture combined with artificial tears for patients with dry eye syndrome (DES) and the control groups that addressed artificial tears were analyzed. The main outcomes were tear breakup time (BUT) and Schirmer I test (SIT), assessed as previously described.

RESULTS:

Sixteen randomized or controlled trials met the selection criteria, and 1383 patients with DES were included in this study. The analysis results showed that BUT [Standard mean difference (SMD) = 1.25, 95% confidence interval (CI) (1.14, 1.37), P < .0001], SIT [SMD = 1.55, 95% CI (1.08, 2.02), P < .0001], and corneal fluorescein staining [SMD = -2.08, 95% CI (-2.96, -1.20), P < .00001] significantly improved in the trial groups compared with the control groups. The acupuncture treatment was more effective in reducing the levels of IL-6 (P < .0001) and TNF-α (P < .00001). The overall efficacy rate was better in the trial group than in the control group [odds ratio = 4.09, 95% CI (3.04, 5.51), P < .00001]. However, no significant difference was observed in the ocular surface disease index (P = .15) between the trial and control groups.

CONCLUSION:

The results of this study indicated that acupuncture combined with artificial tears could be considered safe, effective to patients with DES.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndromes de Ojo Seco / Terapia por Acupuntura Tipo de estudio: Clinical_trials / Systematic_reviews Límite: Humans Idioma: En Revista: Medicine (Baltimore) Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndromes de Ojo Seco / Terapia por Acupuntura Tipo de estudio: Clinical_trials / Systematic_reviews Límite: Humans Idioma: En Revista: Medicine (Baltimore) Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos